Chemokines Mnemonics

Difference between cytokines and chemokines Cytokines are small proteins released by cells, the function of which is “cell-signaling“. Chemokines are small cytokines, which functions as a “chemo-attractant“. Types of Chemokines When you go through the structural classification of chemokines, you come accross various arrangements of… Read More

Steroid Induced Leukocytosis

Mechanism of Steroid Induced Leukocytosis There are 3 major mechanisms responsible for corticosteroid induced granulocytosis: 1. Demargination of neutrophils from endothelial cells (60% of the rise): Recall the leukocyte adhesion cascade in the chapter of inflammation. L-selectins are present in leukocytes that mediates their rolling… Read More