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Hematology

philadelphia chromosome
PGMEE, MBBS, MD/MS

Oncogenic Translocations to remember

Epomedicine May 23, 2019 6 Comments HematologyPathology

t(8;14): Burkitt’s lymphoma t(14;18): Follicular lymphoma t(11;14): Mantle cell lymphoma t(11,18): Marginal zone lymphoma (MALT lymphoma) t(9;22): CML (Philadelphia chromosome), Bad prognosis ALL t(8;21): AML…

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coombs test
PGMEE, MBBS, MD/MS

Coomb’s test : Mnemonic

Dr. Sulabh Kumar Shrestha, MS Orthopedics May 23, 2019 No Comments HematologyObGyn

Components of Coomb’s test: Mnemonic: ABCD A: Antibody (to be detected) B: Blood antigen (RBC) C: Coomb’s reagent (Anti-antibody) D: Detect agglutination Direct Coomb’s/Antiglobulin test…

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protein-c-s mnemonic
PGMEE, MBBS, MD/MS

Protein C and S pathway – Mnemonic

Dr. Sulabh Kumar Shrestha, MS Orthopedics May 23, 2019 No Comments Hematology

Factor Va and VIIIa are different in coagulation cascade. They are the co-factors for factor Xa and IXa respectively. Another mnemonic: protein C Cuts Coagulation…

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hematopoiesis
PGMEE, MBBS, MD/MS

Hematopoietic growth factors list with mnemonics

Dr. Sulabh Kumar Shrestha, MS Orthopedics May 23, 2019 No Comments HematologyPathologyPhysiology

a. SCF (Steel factor): Multipontent stem cells b. IL-3: Myeloid stem cells (“3” turned down looks like “m“) c. IL-7: Lymphoid stem cell (“L” turned…

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PGMEE, MBBS, MD/MS

Working formulation of NHL (Mnemonic)

Epomedicine Jan 16, 2019 No Comments HematologyOncologyPathology

All follicular except large cell: Low grade All diffuse: Intermediate grade Blastic and non-cleaved: High grade

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erythropoiesis
PGMEE, MBBS, MD/MS

Erythropoiesis Simplified

Epomedicine Sep 2, 2017 No Comments HematologyPhysiology

Hemoglobin Switching mnemonics 1st to appear: Embryonic hemoglobin (Gower and Portland) Switch from fetal hemoglobin to adult hemoglobin: “Gamma goes, Beta becomes, Alpha always” Fetal hemoglobin: α2γ2…

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erythropoietin mechanism
PGMEE, MBBS, MD/MS

Erythropoietin (EPO) Physiology

Epomedicine Sep 2, 2017 No Comments HematologyPhysiology

Structure of erythropoietin (EPO) Glycoprotein hormone 165 amino acids Molecular mass – 30 kDa Site of production/synthesis of erythropoietin (EPO) Kidneys (75-90%): Peritubular interstitial cells…

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PGMEE, MBBS, MD/MS

Aplastic Anemia : Review notes

Epomedicine Jul 11, 2017 No Comments HematologyInternal medicinePathologyPediatrics

Definition        Failure of bone marrow to produce peripheral blood cells and its progenitors Etiology The following illustration gives a brief idea about the etiological factors…

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