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Pharmacology

USMLE, PGMEE, MBBS, MD/MS

Bisphosphonate Pharmacology

Epomedicine Sep 24, 2020 No Comments Musculoskeletal systemPharmacology

Classification Non-nitrogen containing (1st generation): Etidronate Clodronate Tiludronate Nitrogen containing (2nd and 3rd generation): a. 2nd generation (alky-amino nitrogen containing): Pamidronate Alendronate Ibadronate Olpadronate b.…

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USMLE, PGMEE, MBBS, MD/MS

Antimicrobial Mechanism of Actions – Everything you need to know

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Sep 13, 2020 1 Comment Infectious diseasePharmacology

Cell Wall Synthesis Inhibitors A peptidoglycan monomer consists of 2 joined amino-sugars, N-acetyl glucosamine (NAG) and N-acetyle muramic acid (NAM), with a pentapeptide coming off…

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Clinical Skills and Approaches

Drug Eruptions – When the Solution becomes Problem

Dr. Kanwal Mushtaq, MBBS Jun 18, 2020 No Comments DermatologyPharmacology

Before we start to develop our understanding of the drug eruptions. Let’s first lay down the foundation by clearing some basic concepts. What is an…

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USMLE, PGMEE, MBBS, MD/MS

Antibiotic Spectrums : Cheat sheet

Epomedicine May 20, 2020 No Comments General conceptsPharmacology

Gram positive and Gram negative Amoxicillin-clavulanate Tazobactam-piperacillin Carbapenem: Ertapenen, Imipenem, Meropenem Cefuroxime Cefotaxime Ceftriaxone Anaerobes Amoxicillin-clavulanate Tazobactam-piperacillin Carbapenems Clindamycin Metronidazole Pseudomonas Tazobactam-piperacillin Carbapenems (except Ertapenem)…

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USMLE, PGMEE, MBBS, MD/MS

Calcium Channel Blockers : Mnemonic

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Sep 20, 2019 No Comments Cardiovascular systemPharmacology

Dihydropyridines Mnemonics:a. D for “-dipine”b. D for Dilation of vessels Nifedipine Nicardipine Isradipine Felodipine Amlodipine Non-dihydropyridines Mnemonics:a. N-D for Non “-dipines”b. N-D for Node supression…

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USMLE, PGMEE, MBBS, MD/MS

Simplified Guide to Statin Therapy

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Aug 15, 2019 No Comments Cardiovascular systemInternal medicinePharmacology

Statins Equivalent Dose Mnemonic: PRASLPF 2-5-10-20-40-40-80 Pituvastatin 2 mg Rosuvastatin 5 mg Atorvastatin 10 mg Simvastatin 20 mg Lovastatin 40 mg Pravastatin 40 mg Fluvastatin…

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USMLE, PGMEE, MBBS, MD/MS

Beta-Blockers : Mnemonics

Epomedicine Aug 12, 2019 No Comments Cardiovascular systemPharmacology

We have 1 heart and 2 lungs. a. B1 – heartb. B2 – bronchial wall Cardioselective (B1) vs Non-selective (B1 and B2) beta blockers Beta…

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USMLE, PGMEE, MBBS, MD/MS

Pharmacokinetics Mnemonics

Epomedicine Aug 12, 2019 No Comments General conceptsPharmacology

The most important pharmacokinetic parameters from a dosing point of view are: The clearance (CL) – determines the maintenance dose-rate The volume of distribution (Vd)…

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