Classification Non-nitrogen containing (1st generation): Etidronate Clodronate Tiludronate Nitrogen containing (2nd and 3rd generation): a. 2nd generation (alky-amino nitrogen containing): Pamidronate Alendronate Ibadronate Olpadronate b.…
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Cell Wall Synthesis Inhibitors A peptidoglycan monomer consists of 2 joined amino-sugars, N-acetyl glucosamine (NAG) and N-acetyle muramic acid (NAM), with a pentapeptide coming off…
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Before we start to develop our understanding of the drug eruptions. Let’s first lay down the foundation by clearing some basic concepts. What is an…
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Gram positive and Gram negative Amoxicillin-clavulanate Tazobactam-piperacillin Carbapenem: Ertapenen, Imipenem, Meropenem Cefuroxime Cefotaxime Ceftriaxone Anaerobes Amoxicillin-clavulanate Tazobactam-piperacillin Carbapenems Clindamycin Metronidazole Pseudomonas Tazobactam-piperacillin Carbapenems (except Ertapenem)…
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Dihydropyridines Mnemonics:a. D for “-dipine”b. D for Dilation of vessels Nifedipine Nicardipine Isradipine Felodipine Amlodipine Non-dihydropyridines Mnemonics:a. N-D for Non “-dipines”b. N-D for Node supression…
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Statins Equivalent Dose Mnemonic: PRASLPF 2-5-10-20-40-40-80 Pituvastatin 2 mg Rosuvastatin 5 mg Atorvastatin 10 mg Simvastatin 20 mg Lovastatin 40 mg Pravastatin 40 mg Fluvastatin…
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We have 1 heart and 2 lungs. a. B1 – heartb. B2 – bronchial wall Cardioselective (B1) vs Non-selective (B1 and B2) beta blockers Beta…
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The most important pharmacokinetic parameters from a dosing point of view are: The clearance (CL) – determines the maintenance dose-rate The volume of distribution (Vd)…
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