1. Haemostasis (immediate): In response to exposed collagen, platelets aggregate at the wound and degranulate, releasing inflammatory mediators. Clotting and complement cascades activated. Thrombus formation and reactive…
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Quick review/Mnemonic: PAPP-A is decreased in all trisomies.Nuchal translucency is increased in all trisomies. Inhibin A is only increased in Down’s syndrome.Beta-HCG is increased in…
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Remember SPACE LEAF for Revised Jone’s Criteria (2015). Major criteria Mnemonic: SPACE Subcutaneous nodules Pancarditis Arthritis (Polyarthritis; for moderate to high-risk population – monoarthritis also…
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The order of the nephron defects in Bartter, Gitelmann and Liddle syndrome follows alphabetical order. Bartter: Thick ascending LOHGitelmann: Distal tubuleLiddle: Collecting duct a. Bartter…
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The rhymes Two and Three – SLEThree and Four – Sugar HLA DR-2 and DR-3: SLE HLA DR-2: Japanese SLE HLA DR-3: Caucasian SLE HLA…
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Location in bone a. Epiphysis: Pediatric: Chondroblastoma Adult: Giant cell tumor (GCT) or Osteoclastoma Other differentials: Osteomyelitis, Paget disease b. Metaphysis: Medullary: Simple (unicameral) bone…
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t(8;14): Burkitt’s lymphoma t(14;18): Follicular lymphoma t(11;14): Mantle cell lymphoma t(11,18): Marginal zone lymphoma (MALT lymphoma) t(9;22): CML (Philadelphia chromosome), Bad prognosis ALL t(8;21): AML…
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a. SCF (Steel factor): Multipontent stem cells b. IL-3: Myeloid stem cells (“3” turned down looks like “m“) c. IL-7: Lymphoid stem cell (“L” turned…
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