Coronaviridae, one of the families of viruses which are known to cause diseases in mammals and birds ranging from the common cold to Severe Acute…
Explore more Novel Coronavirus Disease (CoViD-19) – “An Old Family with a New Disease”
Microbiology
Medical Significance of Bedbugs
Two species of bedbugs bite people: the common bedbug (Cimex lenticularis) and the tropical bedbug (Cimex hemipterous). These bugs are called udus (उडुस) in Nepali…
Explore more Medical Significance of Bedbugs
Antigenic Shift and Drift
Antigenic Drift Nature of antigenic variation: Minor Mechanism: Gradual accumulation of amino acid substitutions due to point mutation in the hemagglutinin (H) and neuraminidase (N)…
Explore more Antigenic Shift and Drift
Bedside Cold Agglutinin Test for Mycoplasma
Definition of Cold Agglutinin Cold agglutinins are polyclonal IgM that have specificity against the I-antigen on red cells, and often there is light chain restriction,…
Explore more Bedside Cold Agglutinin Test for Mycoplasma
Rickettsial Diseases Made Easy
Important features of Rickettsia and Rickettsial Diseases Obligate intracellular parasites like Chlamydia – can survive only in host cells Cannot produce their own ATP, so…
Explore more Rickettsial Diseases Made Easy
Interpreting Hepatitis B Serology in 5 Easy steps
Hepatitis B surface antigen (HBsAg) Appears during incubation period (1-6 months), 2-7 weeks prior to symptoms. Peaks when the patient is most ill. Becomes undetectable…
Explore more Interpreting Hepatitis B Serology in 5 Easy steps
Polymerase Chain Reaction (PCR) Made Easy
What is Polymerase Chain Reaction ? It is a process of artificial DNA replication (amplification of a selected part of DNA). As the name suggests:…
Explore more Polymerase Chain Reaction (PCR) Made Easy
Complement System Simplified
The complement system is composed of about 20 different proteins released into the blood after production in the liver. They interact in coordinated and regulated way…
Explore more Complement System Simplified