Normal values Step 1: pH Step 2: pCO2 Step 3: HCO3- Step 4: Determine compensation If there is metabolic acidosis or alkalosis, determine if there…
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Biochemistry
Calcium Metabolism
Functions Mnemonic: Six ‘C’s Contraction of muscles (Coupling of excitation-contraction) Conduction in nerves Cardiac function Coagulation in blood (Co-factor) Communication (intracellular messengers) for hormones, autacoids…
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Amylase and Lipase in Acute Pancreatitis
Test Rise Peak Return to baseline Lipase 4-6 hours 48 8-14 days Amylase 2-4 hours 24-48 5-7 days Serum lipase elevation has a better diagnostic…
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Tyrosinemia Enzymes : Mnemonic
Mnemonic: FAHeem TATtooes because of Histrionic Personality Disorder (HPD) Tyrosine is necessary for biosynthesis of catecholamines, thyroid hormones and melanin pigment. 1. Tyrosinemia type I (Tyrosinosis/Hepatorenal…
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Competitive, Non-competitive and Uncompetitive Inhibitors
Vmax is the maximum velocity, or how fast the enzyme can go at full ‘‘speed.’’ Vmax is reached when all of the enzyme is in…
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Beta-oxidation of Fatty Acids : Simplified
Fatty Acid Activation (Cytoplasm) Before undergoing oxidation, fatty acid must be activated first by conversion into Acyl-CoA by the action of Fatty Acyl-CoA synthase (thiokinase).…
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Fatty Acid Synthesis : Simplified
Enzymes: Fatty acid synthase (6 enzymes and 1 Acyl carrier protein molecule) Acetyl-CoA carboxylase (rate-limiting enzyme) Starting material: For palmitate synthesis: Acetyl-CoA For odd number…
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Structure of Fatty acids and Derivatives : Simplified
Structure Saturated fatty acid: Single bond (“S” for saturated and single bond) Unsaturated fatty acid: Double bond(s), i.e. “D” for Double bonds, Decreased melting temperature…
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