Amino Acids Mnemonics

What are amino acids ?

Amino acids are molecules containing:

  1. An amine group
  2. A carboxylic acid group
  3. A side chain that varies between different amino acids

amino acid structure

Assign the names of these amino acids to 20 different alphabets

The technique that you are going to use to remember all these are given just below the list.

  • A – Alanine
  • B: ⊗
  • C: Cysteine
  • D: Aspartate
  • E: Glutamate
  • F: Phenylalanine
  • G: Glycine
  • H: Histidine
  • I: Isoleucine
  • J: ⊗
  • K: Lysine
  • L: Leucine
  • M: Methionine
  • N: Aspargine
  • O: ⊗
  • P: Proline
  • Q: Glutamine
  • R: Arginine
  • S: Serine
  • T: Threonine
  • U: ⊗
  • V: Valine
  • W: Tryptophan
  • X: ⊗
  • Y: Tyrosine
  • Z: ⊗

Technique to remember this representative alphabets

amino acid structures
From compoundchem.com

1. Amino acids with unique 1st letter:

  • Cysteine (C)
  • Histidine (H)
  • Isoleucine (I)
  • Methionine (M)
  • Valine (V)
  • Serine (S)

2. 1st letter for more than one amino acids – but reserved for representation of these:

  • Alanine (A)
  • Glycine (G)
  • Leucine (L)
  • Proline (P)
  • Threonine (T)

3. Phonetically suggestive:

  • Arginine (R-ginine)
  • Phenylalanine (F-enylalanine)
  • Tyrosine (tYrosine)
  • Tryptophan (W-structure of tryptophan)

4. Others:

  • Aspartate or Aspartic acid (asparDic)
  • Asparagine (aspargiN)
  • Glutamate or Glutamic acid (gluE-tamate)
  • Glutamine (Q-tamine)
  • Lysine (K is near L)

Amino acids Classified with Mnemonics

A. Basis of Structure:

1. Aliphatic side chains: GAVLI

  • Glycine, Alanine, Valine, Leucine, Isoleucine

2. With OH group: STY

  • Serine, Threonine, Tyrosine

3. Acidic: AAGG

  • Aspartate, Aspargine, Glutamate, Glutamine

4. Sulphur containing: CM

  • Cysteine, Methionine

5. Basic: HIstory of ARGentina was Lie

  • Histidine, Arginine, Lysine

6. Aromatic: HTTP

  • Histidine, Tryptophan, Tyrosine, Phenylalanine

7. Imide:

  • Proline

B. Essential and Non-essential:

1. Essential Amino acids: PVT TIM HALL

  • Phenylalanine
  • Valine
  • Threonine
  • Tryptophan
  • Isoleucine
  • Methionine
  • Histidine
  • Arginine
  • Lysine
  • Leucine
  • Semi-essential are Histidine and Arginine

2. Non-essentia Amino acidsl: Rest of the 10 amino acids

C. Metabolic Fate of Amino acids:

1. Ketogenic: Lysine, Leucine

2. Partially Ketogenic/Glucogenic: Isoleucine and other 3 aromatic amino acids (Tyrosine, Tryptophan, Phenylalanine)

3. Glucogenic: Rest

D. Polarity:

1. Polar with no charge on R: STY: glutamine, aspargine, cysteine, glycine

2. Polar with +ve R: Arginine, Histidine, Lysine (Basic)

3. Polar with -ve R: Aspartate, Glutamate (Acidic)

4. Non-polar: Rest

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