All follicular except large cell: Low grade
All diffuse: Intermediate grade
Blastic and non-cleaved: High grade
Working formulation of NHL (Mnemonic)
PGMEE, MRCS, USMLE, MBBS, MD/MS
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How Metformin Causes Vitamin B12 deficiency?
Multiple studies have shown that metformin reduces serum B12 levels in 10–30% of patients. The effect increases with the duration of the therapy. Decrease in vitamin B12 absorption and levels following metformin use typically starts as early as the 4th month. Mechanisms of Vitamin B12 deficiency with Metformin Use: It…
PGMEE, MRCS, USMLE, MBBS, MD/MS
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Perioperative Management of Venous thromboembolism (VTE)
Recommended duration of anticoagulant prophylaxis The recommendations are as follows: 1. Provoked DVT (with reversible surgical or nonsurgical provoking factor): 3 months 2. Unprovoked isolated distal DVT (has low risk of recurrence): 3 months 3. Unprovoked proximal DVT or PE: Indefinite therapy if D-dimer positive after 1 month after 3 months of therapy or second VTE…
PGMEE, MRCS, USMLE, MBBS, MD/MS
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Kienbock’s Disease : Mnemonic Approach
Etiology Mnemonic: RSTUV Lichtman Classification and Management Stage Description Treatment Mnemonic: ABCD Mnemonic: ABCD I Abnormal MRI (decreased T1 intensity; variable T2 intensity) or scintigraphy Analgesics + immobilization II Bone sclerosis ± Bone breaks (fracture lines) Bony procedures:1. Negative or Neutral ulnar variance: Joint levelling procedure (Radius shortening osteotomy; Ulnar…