Sickle Cell Disease (SCD) is a hereditary disorder of hemoglobin synthesis caused by a mutation in the globin gene that changes the sixth amino acid from glutamic acid to valine resulting in abnormal sickling (rigid, inflexibled and sickle-shaped) of Red Blood Cells (RBCs) under low oxygen conditions. Sickle cell anemia…
Motor march phenomenon is a sign of reinnervation like Hoffman-Tinel’s sign which has been discussed earlier. Observed in: Axonotmesis Repaired Neurotmesis Not observed in: Neuropraxia Motor march phenomenon: As the re-innervation of injured nerve proceeds, the muscles nearest to the site of injury recovers first followed by distal ones sequentially…