In medical schools, we learn many things without knowing the actual reason behind it. One of them is the pre-transfusion fever in a patient being planned for blood transfusion which is considered as a contraindication for it in many departments and health centers. So, the questions that came into my…
Opioid Adverse Effects – Mnemonic
Mnemonic: MORPHINES 1. Miosis Mechanism: Stimulation of Edinger-Westphal nucleus of Cranial nerve III 2. Orthostatic hypotension Mechanism: Vasodilation due to – Direct action decreasing tone of blood vessels Histamine release Depression of vasomotor center 3. Respiratory depression Mechanism: Inhibits respiratory center in a dose-dependent manner (neurogenic, hypercapneic and hypoxic drives…
L-PRF for Chronic Wounds
L-PRF (Leukocyte-platelet rich fibrin) is a second generation platelet reach concentrate where autologous platelets and leukocytes are present in a 3D fibrin mesh which is used as a scaffold by surrounding host cells and which slowly releases growth factors and glycoproteins (≥ 7 days). It is processed without the anticoagulant,…
Diagnosis of Spinal Instability (White & Panjabi) : Mnemonic
Mnemonic: Remember 4 D common to all + 3 D for C-spine and 1 D for L-spine Diagnosis requires: Score >4 Denis column disruption: Anterior column destroyed or unable to function (2 points) Posterior column destroyed or unable to function (2 points) Deformity: Will have a maximum score of 4…
Ectrodactyly or Lobster-claw syndrome : A Case Report
Ectrodactyly is an autosomal dominant ectodermal dysplasia presenting as bilateral congenital malformed hands and feet [1]. It affects about 1 in 90,000 births with males and females equally as likely to be affected. It is characterized by transverse terminal aphalangia or partial to total absence of the distal segments of…
Pharmacology of Carbapenems : Mnemonics
Commonly used Carbapenems Mnemonic: MEDIC Meropenem Ertapenem Doripenem Imipenem/Cilastatin (renal dehydropeptidase I inhibitor) Besides these, there are other drugs like tebipenem (1st oral carbapenem), panipenem, tomopenem (has MRSA activity), etc. which fall under carbapenems. Coverage As the name suggests, they have carbapenems attached to beta-lactam ring which provides protection against…
Scheurmann’s Disease : Mnemonic
Mnemonic: Remember “S” for Scheurmann Structural kyphosis (sagittal deformity) of thoracic or thoracolumbar spine Skeletally immature sons (0.4-10% of adolescents between 10-14 years; onset with prepubertal growth spurt; M:F = 2-7:1) Strong hereditary (genetic) predisposition and Several theories: Scheurmann’s vertebral epiphyseal disturbance theory Schmorl’s nodes (herniation of disc material into…
FDA Pregnancy Drug Risk Categories : Mnemonic
We have simplified the information above as following: Category A: Adequate Anthropoid (Human) studies and Absolutely safe (No risk in controlled human studies) Category B: Bounded (limited) human studies and safe in Beast (animal) studies; Better to use (No risk in other studies) Category C: Catastrophic effects in animals and…