You must be asking yourself – “how to remember the TNM staging system?” and looking here and there for mnemonics only to find nowhere. Understanding the oncoanatomy helps to understand the staging system of the cancers. Tumor Status (T) T1 T2 T3 T4 Depth of invasion Solid organs Confined Capsule,…
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Medical knowledge in bullet points with understandable language, simplified images and graspable mnemonics.

Hodgkin’s Lymphoma – Staging and Prognostic Factors
Costwold Modified Ann-Arbor Staging I: 1 Lymph Node (LN) region (I) or 1 Extralymphatic site (IE) II: On the same side of diaphragm – ≥2 LN region (II) or Localized Extralymphatic extension + ≥1 LN region (IIE) III: On both the sides of diaphragm – LN regions (III) ± Spleen involvement (IIIS) ± Localized…

Embryology Week 4: Rule of Fours
Second week is the week of twos. In third week trilaminal germ disc is formed. And now, here I have attempted to fit the fourth week in development of embryo as the week of fours. Four folds of the embryo The embryo undergoes: Lateral folding Cranio-caudal folding It forms four…

Lung Development – Embryology Made Easy
Remember the mnemonic – “Every Premature Child Takes Air“. The development of lungs comprises of 5 distinct stages: Embryonic (3-8 weeks, i.e. embryonic period) Pseudoglandular (5-16 weeks) Canalicular (16-26 weeks) Terminal saccular (26-36 weeks) Alveolar (36 weeks to 40 weeks and continues to childhood) The first and last stages, i.e….

Diaphragm and Body Cavities Development – Embryology Made Easy
Let’s go back to the 4th week during the development of heart. The primitive intraembryonic coelom forms in the lateral and cardiogenic mesoderm during 4th week of development. Like the heart fields, the intraembryonic coelom has a horse-shoe configuration during this period: A thick mesodermal plate called “septum transversum” lies…

Cloaca in Embryology – Urogenital and Anal Development
Cloaca literally meas a “sewer” – a coduit for carrying of drainage water and waste matter. The cloaca in human fetus have the same function, i.e. carries waste porducts in the from of urine and stool. Cloaca: Common chamber for the hindgut and urinary systems. Formation of cloaca: Endodermal – incorporation…

Fetal Circulation Made Easy
Following are the important features of fetal circulation: 1. Placenta plays the role of lungs; lungs are not functional: Like pulmonary veins, left umbilical vein carries highly oxygenated blood from placenta to heart. Like pulmonary artery, right and left umbilical arteries braing deoxygenated blood to placenta. 2. Mixing potentially occurs…

Renal (Kidney) Development – Embryology Made Easy
Kidney development occurs chronologically from cranial to caudal direction from urogenital ridge (intermediate mesoderm) in 3 different phases. Intermediate mesoderm → urogenital ridge (longitudinal elevation along dorsal body wall) → nephrogenic cord → Pronephros, Mesonephros and Metanephric mesoderm/blastema Remember the embryology of brain – from cranial to caudal, the primordial…