Statistical hypotheses Null hypothesis (H0): No difference or relation exists; e.g. Treatment A is not better than Treatment B Alternative or research hypothesis (H1): Some difference or relation exists, e.g. Treatment A is better than Treatment B Statistical errors Type I error (alpha): False positive (Falsely rejecting Null-hypothesis; i.e. null…
Category: PGMEE, MRCS, USMLE, MBBS, MD/MS
Medical knowledge in bullet points with understandable language, simplified images and graspable mnemonics.
Baye’s theorem derived PPV and NPV
Let’s unveil the mathematics behind the relation between: Prevalence (Pre-test probability) Predictive value (Post-test probability) Sensitivity Specificity SYMBOLS: Total screened population = nPrevalence = PSensitivity = SnSpecificity = SpTrue positive = TPTrue negative = TNFalse positive = FPFalse negative = FNWith disease = D+Without disease = D-Positive predictive value =…
Screening tests in Series and Parallel
A. Parallel testing 2 screening tests are applied simultaneously: So, this test will have: B. Series testing After the 1st screening test is conducted, those who test positive are only tested with the 2nd screening test: So, this test will have: Formulae for combined specificity and sensitivity A. Parallel testing:…
Sustainable Development Goal 3 – Points to Remember
Total SDG goals: 17 Time frame: 2016-2030 Goal 3: Good health and well beings for all ages Important targets of Goal 3 (Targeted by 2030) A. Maternal and Child health (MCH) Mnemonic: 12 letters in “NEONATE DEATH or NEWBORN DEATH“. 1. NMR reduction target: 122. U5MR reduction target: 12 X…
Key Health Indicators of Nepal to Remember (NDHS, 2022)
These rates, ratios and proportions are often questioned in PGMEE, pediatrics, obstetrics and preventive and social medicine (PSM) or community medicine examinations. NDHS = National Demographic and Health Survey a. Neonatal mortality rate (NMR): 21 per 1000 live births (i.e. 3/4 of infant deaths) b. Infant mortality rate (IMR): 28…
Oncogenic Translocations to remember
t(8;14): Burkitt’s lymphoma t(14;18): Follicular lymphoma t(11;14): Mantle cell lymphoma t(11,18): Marginal zone lymphoma (MALT lymphoma) t(9;22): CML (Philadelphia chromosome), Bad prognosis ALL t(8;21): AML M2 t(15;17): AML M3 (Promyelocytic AML) t(X;18): Synovial cell sarcoma t(11;22): Ewing’s sarcoma t(12;21): Pre-B ALL (good prognosis ALL) t(4;11) and t(1;19): Bad prognosis ALL
Coomb’s test : Mnemonic
Components of Coomb’s test: Mnemonic: ABCD A: Antibody (to be detected) B: Blood antigen (RBC) C: Coomb’s reagent (Anti-antibody) D: Detect agglutination Direct Coomb’s/Antiglobulin test (DAT or DCT): Mnemonic: In DAT/DCT we take A+B from patient and add C [(A+B) + C] Another Mnemonic: DCBA (Direct Coomb’s detect Blood Bound…
Protein C and S pathway – Mnemonic
Factor Va and VIIIa are different in coagulation cascade. They are the co-factors for factor Xa and IXa respectively. Another mnemonic: protein C Cuts Coagulation by Cutting Cofactors (Va and VIIIa) Protein S is cofactor for protein S. Protein C and S pathway using the mnemonic: Time To: Thrombin (factor…