We have 1 heart and 2 lungs. a. B1 – heartb. B2 – bronchial wall Cardioselective (B1) vs Non-selective (B1 and B2) beta blockers Beta…
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Pharmacology
Pharmacokinetics Mnemonics
The most important pharmacokinetic parameters from a dosing point of view are: The clearance (CL) – determines the maintenance dose-rate The volume of distribution (Vd)…
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Acyclovir Post-exposure Prophylaxis for Varicella: Is it helpful?
Dose: 80 mg/kg/day in 4 divided doses for 7 days; maximum 800 mg 4 times a day Time to start prophylaxis: 7-10 days after exposure…
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Competitive, Non-competitive and Uncompetitive Inhibitors
Vmax is the maximum velocity, or how fast the enzyme can go at full ‘‘speed.’’ Vmax is reached when all of the enzyme is in…
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Signaling Pathways of Hormones : Mnemonic
cAMP Mechanism Mnemonic: FLAT CAMP B-HCGS Remember “B-FLAT” mnemonic for hormones secreted by basophilic cells of the anterior pituitary. This is the same “FLAT” here.…
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Long term PPI use : Associated risks
Proton pump inhibitors (PPI) are often self-prescribed by the patients and since PPIs are available over-the-counter, patients can have free access to them and for…
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Ethambutol Induced Optic Neuropathy
Mechanism of Ethambutol induced optic neuropathy Ethambutol is metabolized to a chelating agent. The chelating agent formed then may impair the function of metal-containing mitochondiral…
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Prescribing Opioids for Chronic Pain
Recommendations for Prescribing Opioid in Chronic pain 1. 1st line of therapy in chronic pain outside of active cancer, palliative or end of life care…
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