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Pharmacology

acyclovir
Blog

Acyclovir Post-exposure Prophylaxis for Varicella: Is it helpful?

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Jun 11, 2019 No Comments DermatologyPediatricsPharmacology

Dose: 80 mg/kg/day in 4 divided doses for 7 days; maximum 800 mg 4 times a day Time to start prophylaxis: 7-10 days after exposure…

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inhibition_Lineweaver_Burk
USMLE, PGMEE, MBBS, MD/MS

Competitive, Non-competitive and Uncompetitive Inhibitors

Epomedicine Aug 10, 2018 No Comments BiochemistryGeneral conceptsPharmacology

Vmax is the maximum velocity, or how fast the enzyme can go at full โ€˜โ€˜speed.โ€™โ€™ Vmax is reached when all of the enzyme is in…

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second messengers
USMLE, PGMEE, MBBS, MD/MS

Signaling Pathways of Hormones : Mnemonic

Epomedicine Jul 17, 2018 No Comments Endocrine systemPharmacologyPhysiology

cAMP Mechanism Mnemonic: FLAT CAMP B-HCGS Remember “B-FLAT” mnemonic for hormones secreted by basophilic cells of the anterior pituitary. This is the same “FLAT” here.…

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chronic PPI use
USMLE, PGMEE, MBBS, MD/MS

Long term PPI use : Associated risks

Epomedicine Mar 1, 2018 No Comments Gastrointestinal systemInternal medicinePharmacology

Proton pump inhibitors (PPI) are often self-prescribed by the patients and since PPIs are available over-the-counter, patients can have free access to them and for…

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Visual field defect ethambutol
USMLE, PGMEE, MBBS, MD/MS

Ethambutol Induced Optic Neuropathy

Epomedicine Mar 27, 2017 No Comments Nervous systemOphthalmologyPharmacology

Mechanism of Ethambutol induced optic neuropathy Ethambutol is metabolized to a chelating agent. The chelating agent formed then may impair the function of metal-containing mitochondiral…

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opioid algorithm
Clinical Skills and Approaches

Prescribing Opioids for Chronic Pain

Epomedicine Jan 12, 2017 No Comments Internal medicineOncologyPharmacology

Recommendations for Prescribing Opioid in Chronic pain 1. 1st line of therapy in chronic pain outside of active cancer, palliative or end of life care…

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opioid receptors
USMLE, PGMEE, MBBS, MD/MS

Opioid Receptors Mnemonic

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Jan 4, 2017 1 Comment AnesthesiaNervous systemPharmacology

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. Mu (ยต) Receptor (MOP) Mnemonic: MU CARDS Miosis eUphoria Constipation Analgesia…

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antidepressant side effects
USMLE, PGMEE, MBBS, MD/MS

Antidepressants Made Easy

Epomedicine Jan 4, 2017 No Comments Nervous systemPharmacologyPsychiatry

Tricyclic Antidepressants (TCA) Mnemonic: -pramine, -triptyline, -pin Secondary amines: predominantly norepinephrine reuptake inhibitors Nor-triptyline Desi-pramine Tertiary amines: Ami-triptyline Imi-pramine Clomi-pramine Doxe-pin Irreversible MAO Inhibitors Mnemonic:…

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