Purines and Pyrimidines Bases Purines = 2 rings Adenine Guanine Hypoxanthine (Deaminated Adenine) Adenine to Hypoxanthine deamination is mediated by Adenosine deaminase which is decreased…
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Anticipation in genetics refers to an increase in severity and decrease in age of onset in successive generations, most likely due to increased size of…
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First: Look for Mitochondrial Inheritance Female transmits disease to all the offsprings (both males and females). Male doesn’t transmit the disease and only the females…
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Among the common lysosomal storage disorders: Two of them are Mucopolysaccharidoses (Hunter and Hurler syndrome) Pompe’s disease is Glycogen Storage Disease. Others are Sphingolipidoses. Inheritance…
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Glucose-6-Phosphate central to the 4 major metabolic pathways of glucose, i.e. glycolysis, gluconeogenesis, glycogenesis, glycogenolysis and HMP shunt (Pentose phosphate pathway). Glucose is immediately phosphorylated…
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Once again, I’m back with a biochemistry topic that everyone hates. Let’s try to break the topic, simplify it and cover all the important aspects…
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Synonyms: Monoclonal spike, M-protein spike, Monoclonal band, Monoclonal gammopathy Tests showing M-spike Serum Protein Electrophoresis (SPEP) Urine Protein Electrophoresis (UPEP) Normal SPEP or UPEP Electrophoresis is…
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Propionyl CoA is a common intermediate in catabolism of essential amino acids and odd chain fatty acids. It is also called VOMIT pathway which stands…
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