Enzymes: Fatty acid synthase (6 enzymes and 1 Acyl carrier protein molecule) Acetyl-CoA carboxylase (rate-limiting enzyme) Starting material: For palmitate synthesis: Acetyl-CoA For odd number…
Explore more Fatty Acid Synthesis : Simplified
Biochemistry
Structure of Fatty acids and Derivatives : Simplified
Structure Saturated fatty acid: Single bond (“S” for saturated and single bond) Unsaturated fatty acid: Double bond(s), i.e. “D” for Double bonds, Decreased melting temperature…
Explore more Structure of Fatty acids and Derivatives : Simplified
Understanding Dexamethasone Suppression Test
The Dexamethasone Suppression Test (DST) is based on the principle of negative feedback exerted by steroids on pituitary gland’s ACTH secretion. Negative feedback with exogenous…
Explore more Understanding Dexamethasone Suppression Test
Most Important Urinary Buffer: Phosphate or Ammonia?
There are multiple choice questions (mcq) which asks: What is the most important urinary buffer? And the choices include both the phosphate and ammonia. Different…
Explore more Most Important Urinary Buffer: Phosphate or Ammonia?
DNA Replication Explained With Zipper Model
Imagine DNA as a zipper Prokaryotic DNA as a zipper with single slider (single origin of replication) and Eukaryotic DNA as a zipper with two…
Explore more DNA Replication Explained With Zipper Model
Purine and Pyrimidines : Structure, Synthesis and Metabolism
Purines and Pyrimidines Bases Purines = 2 rings Adenine Guanine Hypoxanthine (Deaminated Adenine) Adenine to Hypoxanthine deamination is mediated by Adenosine deaminase which is decreased…
Explore more Purine and Pyrimidines : Structure, Synthesis and Metabolism
Trinucleotide Repeat Disorders and Anticipation Mnemonics
Anticipation in genetics refers to an increase in severity and decrease in age of onset in successive generations, most likely due to increased size of…
Explore more Trinucleotide Repeat Disorders and Anticipation Mnemonics
Solving Pedigree Analysis in 3 steps
First: Look for Mitochondrial Inheritance Female transmits disease to all the offsprings (both males and females). Male doesn’t transmit the disease and only the females…
Explore more Solving Pedigree Analysis in 3 steps