All Local anesthetics contain suffix “-caine”. Local Anesthetics (LA) can be classified as: Esters and Amides. Esters vs Amides A mnemonic device is that the…Explore more Local Anesthetics Mnemonic
Priming Administration of a small sub-paralyzing dose of non-depolarizing muscular blocking agent (usually 10% of the intubating dose) is given 2-4 minutes before administering a…Explore more Priming, Precurarization and Self taming
Concentration effect The higher the concentration of an inhaled anesthetic, the faster the alveolar concentration approaches the inhaled concentration. This is referred to as concentration…Explore more Concentration effect, Second gas effect and Diffusion hypoxia
Anatomy of Mapleson Breathing Circuit Basically, a mapleson breathing circuit consists of following parts: 1. Face mask (towards patient end) 2. Reservoir bag (towards operator…Explore more Mapleson Breathing Circuit Made Easy
Norepinephrine has numerous effects in sepsis including veno-constriction (increasing preload), arterial constriction (increasing systemic vascular resistance), positive inotropy, improved cardiac output, and improved renal perfusion.…Explore more Early vs Delayed Norepinephrine Use in Septic Shock
Endpoints of resuscitation MAP: > or = 65 mmHg Urine output: > 0.5 ml/kg/hr; despite ↓RBF (Renal Blood Flow) it can be normal due to…Explore more Septic Shock Fluid Resuscitation
International Surviving Sepsis Campaign has recommended Early Goal Directed Therapy for the management of severe sepsis and septic shock. Recently, three large multicenter studies –…Explore more Is there no role of Early Goal Directed Therapy (EGDT) in Sepsis and Septic shock?
Peculiarities of cerebral circulation: 1. Brain and spinal cord is isolated from endothelium by BBB composed of continuous capillaries that limits movement of proteins and…Explore more Head trauma fluid resuscitation