Seven Killer Causes of Fever and Rash Mnemonic: SMARTTT Sepsis Meningococcemia Acute endocarditis Rocky mountain spotted fever Toxic erythemas Toxic epidermal necrolysis Travel-related infections Onset of Rash with “X” Days of Fever Mnemonic: Very Sick Person Must Take Double Eggs Varicella (Chicken pox): 1st day… Read More
Hemoglobin Switching mnemonics 1st to appear: Embryonic hemoglobin (Gower and Portland) Switch from fetal hemoglobin to adult hemoglobin: “Gamma goes, Beta becomes, Alpha always” Fetal hemoglobin: α2γ2 Adult hemoglobin: α2β2 ζ chain α chain ε chain HbE Gower 1 HbE Gower 2 γ chain HbE Portland I HbF… Read More
Structure of erythropoietin (EPO) Glycoprotein hormone 165 amino acids Molecular mass – 30 kDa Site of production/synthesis of erythropoietin (EPO) Kidneys (75-90%): Peritubular interstitial cells Liver (15%; chief source in fetus and neonates): Centrilobular hepatocytes After birth, erythropoietin is not detectable until 8-12 weeks after… Read More
The ear, along the evolution has modified structurally and functionally. In lower animals, they functioned as alarm systems to detect any sounds of the prey or predator so as to fix their vision and also maintain the balance of the body to prevent fall. In… Read More
Definition Failure of bone marrow to produce peripheral blood cells and its progenitors Etiology The following illustration gives a brief idea about the etiological factors of aplastic anemia Now going into each etiological factor: – Autoimmune diseases: – Either they affect all the lineages (autoimmune… Read More
