Potential indications for antibiotic prophylaxis before surgical procedure are:
1. Penetration into gastrointestinal, respiratory and genital lumens
- Clean-contaminated procedures
2. Prosthesis
- Surgical meshes
- Orthopedic hardwares
- Breast and penile implants
3. Presence of infection
- Contaminated surgeries such as elimination of septic foci and manipulations of infected tissues
4. Prolonged surgery
- Additional risk factor
5. Poor patient immunity
- Additional risk factor
Reference: Hasanin A, Mostafa M. The “5-Ps” Mnemonic for Antibiotic Prophylaxis Before Surgery. Anesth Analg. 2025 May 7. doi: 10.1213/ANE.0000000000007596. Epub ahead of print. PMID: 40333465.
