Mnemonic: SACHS GO
1. Spots in macula (Cherry red spots)
2. Ashkenazic jews
3. CNS degeneration
4. Hexosaminidase A enzyme deficiency
5. Storage disorder
6. GM2 ganglioside accumulation
7. Onion skin appearance of lysosomes
Further reading:
HISTORY 1. General Information: 2. Chief complaints: Example: Lower abdominal pain X 2 daysNausea and vomiting X 1 day 3. History of Presenting Illness: “OPQRST” for each symptoms Negative history: Treatment received for the complaint Review of systems: may or may not be related to chief complaint – include only…
Cerebrospinal Fluid (CSF) Production and Absorption CSF is produced by the choroid plexus that lines the ventricles. Choroid plexus = Infoldings of blood vessels of piamater + Modified ciliated ependymal cells Tight junctions of the choroid plexus cells form Blood-CSF barrier. CSF is reabsorbed by arachnoid granulations to enter dural…
Understanding of the Boutonniere and Swan neck deformity requires clear concept of the finger extensor apparatus, which has been discussed here. The extrinsic extensor tendons trifurcate giving a central slip which attaches to the middle phalanx base and two lateral slips which join with lateral band (formed by intrinsic muscles…