Mnemonic: CENTOr
1. Cough absent or Can’t cough = +1
2. Exudates or Enlarged tonsils = +1
3. Nodes (Swollen tender anterior cervical lymph nodes) = +1
4. Temeperature >100.4 F = +1
5. Or:
Methotrexate is a dihydrofolate reductase (DHFRase) inhibitor which inhibits DNA repair, synthesis and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and cells of the urinary bladder are in general more sensitive to its effect. A convenient regimen for Low Dose…
The complement system is composed of about 20 different proteins released into the blood after production in the liver. They interact in coordinated and regulated way to produce biologically active protein products. ACTIVATION OF COMPLEMENT CASCADE The complement cascade can be activated in 3 ways: C3 and C3 CONVERTASE All of…
Among cartilaginous tumors, 2 pathologies can be misleading when trying to reach a correct diagnosis: enchondroma (E), a benign tumor, and low-grade chondrosarcoma (LGC), which is a low-aggressivity malignancy. This can be a problem when deciding treatment because E only requires regular follow-up, but LGC needs surgical treatment. Mnemonic: ABCDE…