Sickle Cell Disease (SCD) is a hereditary disorder of hemoglobin synthesis caused by a mutation in the globin gene that changes the sixth amino acid from glutamic acid to valine resulting in abnormal sickling (rigid, inflexibled and sickle-shaped) of Red Blood Cells (RBCs) under low oxygen conditions. Sickle cell anemia…
There are 2 major triangles in the neck, containing other smaller triangles. 1. Anterior triangle: Midline of neck – Mandible – Anterior border of SCM Posterior triangle: Posterior border of SCM – Trapezius – Clavicle (level V); 2 triangles inside separated by inferior belly of omohyoid Surgically, cervical lymph nodes…
Bone remodeling involves the removal of mineralized bone by osteoclasts followed by the formation of bone matrix through the osteoblasts that subsequently become mineralized. There are 2 prominent concepts of bone remodelling: 1. Hueter-Volkmann law or Delpech’s law: It states that bone growth in the skeletally immature is inhibited in…