The Dexamethasone Suppression Test (DST) is based on the principle of negative feedback exerted by steroids on pituitary gland’s ACTH secretion. Negative feedback with exogenous steroid works if the cause is excessive ACTH secretion from pituitary: 1. Cushing’s disease (pituitary ACTH dependent Cushing’s syndrome): Excessive ACTH secretion by pituitary adenoma…
Under resting conditions, red blood cells move through the pulmonary capillary bed in approximately 0.75 seconds (transit time), although equilibration of oxygen and carbon dioxide takes place in about 0.25 seconds. In a diffusion limited gas exchange situation, the alveolar gas is still equilibrating with the blood cell at the…