Frontal Lobe Area 4 (Precentral gyrus): Primary motor cortex (gigantopyramidal – only area that contains giant pyramidal cells of Betz) Lesion: Contralateral spastic paralysis (UMNL) Area 6 (Superior frontal gyrus; agranular frontal): Premotor cortex and Supplementary motor cortex (Motor planning) Lesion: Apraxia (Unable to perform movements in correct sequence) Area…
Friedreich’s ataxia is a hereditary spinocerebellar degenerative disorder named after German neurologist, Professor Nicholaus Friedreich. Mnemonic: FRIEDREICH’S Ataxia 1. Foot deformity (progressive cavo-varus), Frataxin expression reduced 2. Recessive (autosomal), Repeat of trinucleotide GAA (chromosome 9) 3. Iron accumulation in mitochondria 4. Extensor plantar response 5. Dysarthria (within 5 years of…