Diacerin is a DMOAD (Diseases Modifying Osteoarthritis Drug) –
D – Diarrhea (not recommended in >65 years – more vulnerable to diarrhea)
I – IL-1 Inhibition
A – Anthraquinone
C – Chondroprotective effects
E – Eczema
R – Rashes
I – Increase in hepatic enzymes (contraindicated in patients with history of liver diseases)
N – NSAID like efficacy after 1st month of treatment
Origin of Subclavian artery: Left: Arch of aorta Right: Brachiocephalic artery Extent of Subclavian artery: Arises posterior to sternoclavicular joint and ends at outer border of 1st rib by becoming acillary artery. Divisions of Subclavian artery: 3 parts in relation to Scalenus anterior muscle 1st part (medial to muscle) 2nd…
Upper end of humerus Mnemonic: HGL – 1,3,5 a. Head – by 1 year b. Greater tuberosity – by 3 years c. Lesser tuberosity – by 5 years All 3 centers fuse together by 6 years (1 year after the last center appears) Upper end of femur Mnemonic: HGL –…
Children are not just mini-adults • Higher head to torso ratio: Head injury & Upper C-spine fractures • Light weight – projectile when struck • BSA to Wt. ratio – higher (rapid hypothermia) • Large cardiopulmonary reserves – normal SBP in significant hypovolemia Growth contribution by Proximal & Distal Physes…