Diacerin is a DMOAD (Diseases Modifying Osteoarthritis Drug) –
D – Diarrhea (not recommended in >65 years – more vulnerable to diarrhea)
I – IL-1 Inhibition
A – Anthraquinone
C – Chondroprotective effects
E – Eczema
R – Rashes
I – Increase in hepatic enzymes (contraindicated in patients with history of liver diseases)
N – NSAID like efficacy after 1st month of treatment
There are certain well-known sentences used as a mnemonic to remember the names and arrangement of the 8 carpal bones in 2 rows. She Looks Too Pretty, Try To Catch Her Some Lovers Try Positions That They Cannot Handle So using this mnemonic, we will learn the arrangement of the…
Epidemiology and Clinical features Mnemonic: LMNOP Lower extremity predilection (proximal femur > tibial diaphysis) Male predilection (2:1 to 3:1) Night pain relieved by NSAIDs (absent in osteoblastoma) Osteogenic benign tumor Prostaglandins (PGE2) and Cyclooxygenase (COX1 and 2) release by nidus (explains night pain and response to NSAIDs) 3 Concentric layers…
CAUSES OF INCREASED PIGMENTATION S: Systemic sclerosis H: Hemochromatosis 1* A: Alkaptonuria K: Kala azar A: Arsenicosis H: Hemochromatosis 2* A: Addison’s N: Nelson’s D: Drugs Amiodarone Busulfan Bleomycin Phenytoin Phenothiazine Psoralen SADDLE NOSE S: Sarcoid, Syphilis congenital, Sponastrine dysplasia, Steward granuloma (extranodal NK/T lymphoma, EBV+), Stickler syndrome (chromos 12 mutation, short nose,…