Diacerin is a DMOAD (Diseases Modifying Osteoarthritis Drug) –
D – Diarrhea (not recommended in >65 years – more vulnerable to diarrhea)
I – IL-1 Inhibition
A – Anthraquinone
C – Chondroprotective effects
E – Eczema
R – Rashes
I – Increase in hepatic enzymes (contraindicated in patients with history of liver diseases)
N – NSAID like efficacy after 1st month of treatment
Lateral wall of nasal cavity has: Mnemonic: SPIN 1. Superior meatus: Posterior ethmoidal sinus 2. Inferior meatus: Nasolacrimal duct The sphenoidal sinus drains into spheno-ethmoidal recess (superior to superior concha). All others drain into middle meatus: Mnemonic: AM/FM
Schatzker system is widely accepted and used to classify tibial plateau fractures. It is based on a 2D representation of the fracture. As a general rule, it can be divided into low-energy and lateral tibial plateau variants (types I-III) and high energy variants (type IV-VI). However, it does not include…
Cardiac Cycle Opening and closing of valves When the valve opens, different compartments act as a single chamber (atrio-ventricle or aorto-ventricle). For a blood to flow, pressure in “giver” must be higher then that in “receiver”. Pressure difference opens or closes the valve: Role of atrial contraction in Ventricular filling…