Synonyms: Osteitis deformans Collage of matrix madness Mnemonic: Sixteen “P”s 1. Paramyxovirus infection and inclusions in osteocalsts 2. Pain (most common symptom – localized fractures or nerve compressions) 3. Pelvis (most common site) 4. Polyostotic (more common; 85%) 5. Phases: Active (lytic, mixed, sclerotic) and Inactive 6. Plasma volume expansion…
Category: PGMEE, MRCS, USMLE, MBBS, MD/MS
Medical knowledge in bullet points with understandable language, simplified images and graspable mnemonics.
PGMEE, MRCS, USMLE, MBBS, MD/MS
Osteopetrosis : Mnemonic
Synonyms: Marble bone disease Albers-Schonberg disease (Autosomal dominant form) Mnemonic: OSTEOPETROSIS Osteoclast dysfunction (Carbonic anhydrase II gene mutation or chloride channel dysfunction) Symmetric skeletal sclerosis Thickened cortex with loss of medullary canal diameter (bone in bone appearance) Extramedullary hematopoiesis (aplastic anemia and hepatosplenomegaly) Overgrowth of skull foramina (cranial nerve palsies)…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Rickets Made Easy
Types Type Pathology 25(OH) D 1,25(OH)2 D PTH Ca PO4 ALP Additional clinical findings Treatment Vitamin D deficiency (Nutritional) Hypovitaminosis D 🡢 Hypocalcemia 🡢 Secondary hyperparathyroidism 🡢 Rise of serum calcium towards normal level ↓ ↓ ↑ ↓/= ↓ ↑ Rachitic rosaryBowing of kneesMuscle hypotoniaWaddling gaitDental diseaseLooser zones/Milkman’s fracture (pseudofracture…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Calcium Metabolism
Functions Mnemonic: Six ‘C’s Contraction of muscles (Coupling of excitation-contraction) Conduction in nerves Cardiac function Coagulation in blood (Co-factor) Communication (intracellular messengers) for hormones, autacoids and transmitters Cementing (mineralization) of bone – Compressive strength Distribution Average young adult = 1200 gm calcium 99% in bone as calcium hydroxyapatite 1% in…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Hawkin’s Classification for Talus Fractures : Mnemonic
Mnemonic: NISA 10-50-90-100 Type I – Non-displaced Neck fracture (upto 10% risk of AVN) 1 blood vessel damaged (entering talar neck) Management: 8 weeks in cast and 4 weeks in CAM cast Type II – Type I + Inferior (subtalar) subluxation/dislocation (upto 50% risk of AVN) 2 blood vessels damaged…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Swan neck deformity vs Boutonniere deformity
Alterations in the relationships between the balanced extrinsic and intrinsic musculature of the hand due to trauma or secondary to the effects of systemic disease may cause the development of functional deformities such as a boutonnière or swan-neck deformity. Swan-neck deformity Boutonniere deformity Deformity PIPJ Hyperextension PIPJ Flexion DIPJ Flexion…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Management of Anti-tubercular therapy (ATT) induced Hepatitis
Definition of ATT induced hepatitis ALT > 3 X Normal + Symptoms OR ALT > 5 X Normal without Symptoms Management of ATT induced hepatitis 1. Hold all TB drugs for 7-10 days. Wait before restarting ATT until: Symptoms: Resolve ALT <2.5 X Normal For severe TB, patients should be…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Osteoid Osteoma : Mnemonic
Epidemiology and Clinical features Mnemonic: LMNOP Lower extremity predilection (proximal femur > tibial diaphysis) Male predilection (2:1 to 3:1) Night pain relieved by NSAIDs (absent in osteoblastoma) Osteogenic benign tumor Prostaglandins (PGE2) and Cyclooxygenase (COX1 and 2) release by nidus (explains night pain and response to NSAIDs) 3 Concentric layers…