The Dexamethasone Suppression Test (DST) is based on the principle of negative feedback exerted by steroids on pituitary gland’s ACTH secretion. Negative feedback with exogenous…
Explore more Understanding Dexamethasone Suppression TestAuthor: Epomedicine
Cholangiocarcinoma (Bile Duct Cancer) – Quick Review
This article is in response to the request made by a reader in the comment section. Today, we will try to simplify the biliary tree…
Explore more Cholangiocarcinoma (Bile Duct Cancer) – Quick ReviewMost Important Urinary Buffer: Phosphate or Ammonia?
There are multiple choice questions (mcq) which asks: What is the most important urinary buffer? And the choices include both the phosphate and ammonia. Different…
Explore more Most Important Urinary Buffer: Phosphate or Ammonia?Rosettes in Pathology
Rosette refers to a decoration or pattern resembling a rose. In pathology, rosette refers to aa halo or “spoke-wheel” arrangement of cells around a central structure…
Explore more Rosettes in PathologyPurine and Pyrimidines : Structure, Synthesis and Metabolism
Purines and Pyrimidines Bases Purines = 2 rings Adenine Guanine Hypoxanthine (Deaminated Adenine) Adenine to Hypoxanthine deamination is mediated by Adenosine deaminase which is decreased…
Explore more Purine and Pyrimidines : Structure, Synthesis and MetabolismTrinucleotide Repeat Disorders and Anticipation Mnemonics
Anticipation in genetics refers to an increase in severity and decrease in age of onset in successive generations, most likely due to increased size of…
Explore more Trinucleotide Repeat Disorders and Anticipation MnemonicsSolving Pedigree Analysis in 3 steps
First: Look for Mitochondrial Inheritance Female transmits disease to all the offsprings (both males and females). Male doesn’t transmit the disease and only the females…
Explore more Solving Pedigree Analysis in 3 stepsGlucose 6 Phosphate : Central to Glucose Metabolism
Glucose-6-Phosphate central to the 4 major metabolic pathways of glucose, i.e. glycolysis, gluconeogenesis, glycogenesis, glycogenolysis and HMP shunt (Pentose phosphate pathway). Glucose is immediately phosphorylated…
Explore more Glucose 6 Phosphate : Central to Glucose Metabolism