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Pathology

cellular adaptations
PGMEE, MBBS, MD/MS

Cellular Adaptations

Epomedicine Jun 17, 2016 2 Comments General conceptsPathology

Hypertrophy, Hyperplasia, Atrophy and Metaplasia are the main four types of cellular adaptations. Adaptations are: Reversible changes In the number, size, phenotype, metabolic activity or functions…

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complement protective mechanism
PGMEE, MBBS, MD/MS

Complement Pathway – Explained

Dr. Sulabh Kumar Shrestha, MS Orthopedics Jun 5, 2016 2 Comments General conceptsImmunologyMicrobiologyPathology

The complement system is composed of about 20 different proteins released into the blood after production in the liver. They interact in coordinated and regulated way…

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cholesterolosis of gallbladder
PGMEE, MBBS, MD/MS

Strawberry Gallbladder (Cholesterolosis)

Epomedicine Jun 12, 2015 No Comments Gastrointestinal systemPathologySurgery

Synonyms: Strawberry gallbladder is also known as hyperplastic cholecystoses. Hyperplastic cholecystoses are a spectrum of non-neoplastic proliferative disorders caused by deposition of cholesterol-laden macrophages within…

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PGMEE, MBBS, MD/MS

Mendelian Inheritance : Basis of Genetics

Epomedicine Feb 22, 2015 No Comments BiochemistryGeneral conceptsPathology

Some important terminologies Gene:  a functional part of the DNA molecule of a chromosome which directs the synthesis of a specific polypeptide chain. Allele (allelomorph):…

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PGMEE, MBBS, MD/MS

Hypertensive Disorders in Pregnancy – Basics

Epomedicine Aug 30, 2014 No Comments ObGynPathology

Hypertensive disorders in pregnancy is a term that encompass wide range of blood pressure related disorders during pregnancy like gestational hypertension, pre-eclampsia, eclampsia, etc. Blood…

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PGMEE, MBBS, MD/MS

Salmonella Osteomyelitis in Sickle Cell Disease

Epomedicine May 21, 2014 7 Comments OrthopedicsPathologyPediatrics

Sickle Cell Disease (SCD) is a hereditary disorder of hemoglobin synthesis caused by a mutation in the globin gene that changes the sixth amino acid…

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PGMEE, MBBS, MD/MS

Leprosy: Etiopathogenesis, Classification and Complications

Epomedicine Nov 19, 2013 No Comments DermatologyMusculoskeletal systemPathology

Synonyms: Hansen’s disease, Kushta roga, Mezels Definition: Leprosy is a chronic granulomatous disease, caused by Mycobacterium leprae which affects prinicpally the skin and  peripheral nerves.…

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PGMEE, MBBS, MD/MS

Pathology Spotters: Instruments

Epomedicine Nov 14, 2013 No Comments Pathology

Pathology Spotter Series: Instruments Level: Undergraduate (MBBS) A) Spotter 1: Instrument: Paraffin Block Use: Tissue embedding – After adding fixative, biopsies are embedded in paraffin/wax…

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