Inheritance: Autosomal Dominant (AD) Cause: Microsatellite instability (MLH1, MSH2 mismatch repair gene mutation) Types: Amsterdam II Criteria for Diagnosis Mnemonic: 3-2-1-0 rule Colorectal cancers: More likely to be mucinous and right-sided Treatment: Total colectomy with ilio-rectal anastomosis Annual screening: Age 25 onwards or beginning no later than 5 years before…
Tag: Gastrointestinal system
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Carcinoid Tumors : Mnemonic
Origin: Neuroendocrine cells Location: Lungs, Bronchi, Trachea, Gastrointestinal tract Synthesize: Biogenic amines (mainly serotonin which is metabolied to 5-HIAA) 5 Manifestations Mnemonic: 5-HIAAS 1. Heart disease (2/3 patients) 2. Intestinal manifestations 3. Airway obstruction 4. Asthma 5. Skin manifestations Alternative mnemonic: CARCinoid Rule of 1/3 Surgery for appendiceal carcinoid tumor…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Gastric Acid Secretion in Parietal cells: Mechanism
Key player: H+/K+ ATPase or “proton pump” (in canalicular membrane of parietal cells) a. Hydrogen ions are generated within the parietal cell from dissociation of water. The hydroxyl ions formed in this process rapidly combine with carbon dioxide to form bicarbonate ion, a reaction catalyzed by carbonic anhydrase. b. Bicarbonate…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Transpyloric Plane : Mnemonic
Synonyms: Addison’s plane Definition: An imaginary horizontal line (halfway between suprasternal notch and pubic symphysis) through the L1 vertebra, a line that is important when performing radiographic imaging studies. Structures lying in transpyloric plane: Mnemonic: TRANSPYLORIC
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Happy Gut – Happy Life: Everyday Tips To Keep Your Digestive System in Best Shape
Taking good care of your digestive system is essential for your overall health and well-being. After all, your digestive system is a vital component of our general wellness that not only provides our bodies with the necessary nutrients to fuel our daily activities but also helps us absorb essential vitamins…
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Gut Health Matters: Coping with Chronic Digestive Disorders
Living with a chronic digestive disorder can significantly impact your daily life, from managing symptoms to navigating dietary restrictions and emotional challenges. However, with the right coping strategies and a holistic approach to wellness, improving your quality of life and finding relief is possible. Coping with these conditions requires a…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Mnemonic based management of Acute Pancreatitis
Acute pancreatitis along with case based discussion has been already covered earlier here: To remember the initial management of acute pancreatitis, one can remember the mnemonics given below: iPA-NCREAS (Ye et.al.) Investigations: Imaging (CT, MRI or Ultrasonography) Prognostic screen to identify severe pancreatitis Amylase and lipase levels Initial treatment: Nutritional…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Proton Pump Inhibitors (PPI) Pharmacology : Mnemonics
Relative Potency in Omeprazole Equivalent (OE) Mnemonic: PLOwER Pantoprazole (4.5 mg OE) Lansoprazole (13.5 mg OE) Omeprazole (20 mg OE) Esomeprazole (32 mg OE) Rabeprazole (36 mg OE) Side effects of PPI Mnemonic: KFC Kidney (Acute interstitial nephritis) Fractures (Hypochlorhydria leading to decreased serum calcium) C. difficile infection Besides, it…