Proton Pump Inhibitors (PPI) Pharmacology : Mnemonics

Relative Potency in Omeprazole Equivalent (OE)

Mnemonic: PLOwER

1. Pantoprazole (4.5 mg OE)
2. Lansoprazole (13.5 mg OE)
3. Omeprazole (20 mg OE)
4. Esomeprazole (32 mg OE)
5. Rabeprazole (36 mg OE)

Side effects of PPI

Mnemonic: KFC

1. Kidney (Acute interstitial nephritis)
2. Fractures (Hypochlorhydria leading to decreased serum calcium)
3. C. difficile infection

Besides, it may also cause nausea, diarrhea and abdominal discomfort as the release of acid into gastric lumen and hence, breakdown of food is interferred.