Mnemonic: ABCD(CD)E(CDE) – 4P
A: Alternate diagnosis of DVT more likely (-2)
B: Bedridden recently >3 days or Big (major) surgery within 3 months (+1)
C: Cancer – treatment or palliation within 6 months (+1)
D: Deep venous involvement:
Mnemonic – CD
- Collateral (non-varicose) superficial veins present (+1)
- Deep venous system tenderness (+1)
E: Edema:
Mnemonic – CDE
- Calf swelling > 3cm compared to other leg – measured 10 cm below tibial tuberosity (+1)
- Denting (pitting) edema of involved leg (+1)
- Entire leg swollen (+1)
4 P:
- Paralysis, Palsy or Plaster immobilization (+1)
- Previous documented DVT (+1)
Rule of 3 – Note the 3 sets of 3:
1. Bedridden for >3 days in 1 month
2. Major surgery in last 3 months
3. More than 3 cm calf enlargement
Pregnant and postpartum women should not be assessed with these criteria and should generally have ultrasonography if DVT suspected.
Interpretation and Applicable algorithm:
1. Score 0 or lower (low risk): 5% risk
2. Score 1-2 (intermediate risk): 17% risk
3. Score 3 or higher (high risk): 17-53% risk
Wells score is low or intermediate – check D-dimer
- D-dimer is normal – send home
- D-dimer is elevated – obtain ultrasound
Wells score is high – obtain ultrasound
- Ultrasound is positive – treat
- Ultrasound is negative – obtain D-dimer
- D-dimer is low – send home
- D-dimer is elevated – repeat ultrasound 1 week
Sensitivity: 77-98%
Specificity: 38-58%
References:
Wells PS, Anderson DR, Bormanis J, et al. Value of assessment of pretrest probability of deep-vein thrombosis in clinical management. Lancet. 1997;350:1795-1798.
Diagnosis of DVT with D-dimer testing and the Wells score (acutecaretesting.org)
Wells’ Criteria for DVT – MDCalc
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He is the section editor of Orthopedics in Epomedicine. He searches for and share simpler ways to make complicated medical topics simple. He also loves writing poetry, listening and playing music.