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Mnemonics, Simplified Concepts & Thoughts

Friedreich’s Ataxia : Mnemonic

Epomedicine, Oct 21, 2022Oct 21, 2022

Last updated on October 21, 2022

Friedreich’s ataxia is a hereditary spinocerebellar degenerative disorder named after German neurologist, Professor Nicholaus Friedreich.

Nicholaus Friedreich
Unknown author, CC BY 4.0, via Wikimedia Commons

Mnemonic: FRIEDREICH’S Ataxia

1. Foot deformity (progressive cavo-varus), Frataxin expression reduced

2. Recessive (autosomal), Repeat of trinucleotide GAA (chromosome 9)

3. Iron accumulation in mitochondria

4. Extensor plantar response

5. Dysarthria (within 5 years of onset), Dorsal column involvement, Diabetes mellitus

6. Reflexes (DTR) absent

7. Early onset (within 25 years of age)

8. Incoordination

9. Cerebellar and Corticospinal tract involvement

10. Hypertrophic cardiomyopathy

11. Scoliosis

12. Ataxia (progressive)

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PGMEE, MRCS, USMLE, MBBS, MD/MS Internal medicinePediatrics

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  1. Amna says:
    Oct 12, 2023 at 1:14 pm

    Very informative and easiest for memorization

    Reply

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Epomedicine. Friedreich’s Ataxia : Mnemonic [Internet]. Epomedicine; 2022 Oct 21 [cited 2025 May 9]. Available from: https://epomedicine.com/medical-students/friedreichs-ataxia-mnemonic/.

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