Diacerin is a DMOAD (Diseases Modifying Osteoarthritis Drug) –
D – Diarrhea (not recommended in >65 years – more vulnerable to diarrhea)
I – IL-1 Inhibition
A – Anthraquinone
C – Chondroprotective effects
E – Eczema
R – Rashes
I – Increase in hepatic enzymes (contraindicated in patients with history of liver diseases)
N – NSAID like efficacy after 1st month of treatment
It is not necessary to memorize each and every step of the process. We will only look into the major events. A. Meaning: Glyco (Sugar) + Lysis (Breaking or splitting) B. Synonyms: Embden-Meyerhof Pathway (EM Pathway) C. Site: Cytoplasm D. Enzyme basics: Kinase: Adds or removes phosphate from substrate (uses…
Besides, for the emergency/urgent surgeries, one needs to evaluate 4 variables in the preoperative cardiac evaluation of the patient for the non-cardiac surgery. We have elaborated the mnemonics used by CasesBlog. These variables can be remembered by the mnemonic PAST. Patient risk Activity level (METs) Surgical risk Test (Stress test)…
Before moving to the concept of wound closure, it is necessary to understand the pathophysiology behind different types of healing. We have covered stages of wound healing in general previously. There are three types of wound healing: Primary intention Secondary intention Tertiary intention Healing by primary intention occurs when the…