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caspase-2 activation
USMLE, PGMEE, MBBS, MD/MS

Mechanism of Apoptosis with Clinical relevance

Epomedicine Jun 17, 2016 No Comments Video General conceptsPathology

Definition of Apoptosis Apoptosis is: Energy (ATP) – dependent, genetically Programmed Cell Death (PCD) in which, Cells activate enzymes that degrade the cells’ own nuclear…

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complement protective mechanism
USMLE, PGMEE, MBBS, MD/MS

Complement System Simplified

Dr. Sulabh Kumar Shrestha, PGY2 Orthopedics Jun 5, 2016 2 Comments Video General conceptsImmunologyMicrobiologyPathology

The complement system is composed of about 20 different proteins released into the blood after production in the liver. They interact in coordinated and regulated way…

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pronator drift positive
Clinical Skills and Approaches

Pronator Drift (Barre’s sign) : Neurological Examination

Epomedicine Jan 22, 2016 5 Comments Video Clinical examinationInternal medicineNervous system

Components of pronator drift Progress from distal to proximal: Downward arm drift Forearm pronation Flexion of the wrist and elbow Method of assessment for pronator…

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patellar clonus
Clinical Skills and Approaches

Clonus : Clinical Examination and Mechanism

Epomedicine Jan 20, 2016 No Comments Video Clinical examinationInternal medicineNervous system

Definition of clonus Clonus is a rhythmic sustained involuntary muscular contractions (generally 5-8 Hz) evoked by sudden passive stretch of the muscle and tendon. Unsustained…

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chest tube isnertion
USMLE, PGMEE, MBBS, MD/MS

Chest Tube Insertion or Tube Thoracostomy

Epomedicine Dec 5, 2015 No Comments Video ProceduresRespiratory systemSurgery

Indications of chest tube insertion Pneumothorax: In any ventilated patient (positive airway pressure will force air into the pleural cavity and produce tension pneumothorax) Tension…

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NG insertion technique
USMLE, PGMEE, MBBS, MD/MS

NG tube insertion

Epomedicine Dec 1, 2015 1 Comment Video Gastrointestinal systemInternal medicineProceduresSurgery

Indications Gastric decompression Gavage (feeding) Gastric lavage (irrigation or dilution of gastric contents) Sampling of the gastric contents for analysis Sometimes used to instil air…

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  • Polytrauma Assessment : Mnemonics
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  • Tendon Transfer Principles : Mnemonic
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