Pharmacology of Clindamycin : Mnemonic

Epomedicine,

Class: Lincosamide

Mechanism of action: Binds 50S subunit of ribosome and inhibits translation – bacteriostatic (Remember the mnemonic: buy AT 30 & CELLS at 50)

Antimicrobial Mechanism of Actions – Everything you need to know
clindamcyin structure

Spectrum: Gram positive and Anaerobes

Mnemonic: PAST

  1. Penicillinase producing Staphylococci
  2. Anaerobes (Bacteroides, Clostridium, Fusobacterium)
  3. Streptococci (Viridans, Pyogenes, Pneumoniae)
  4. Toxoplasma

Uses:

Mnemonic: PAST

  1. Peritonitis, Pelvic abscess, Prophylaxis in dentistry
  2. Aspiration pneumonia, Acne, Anaerobic infections
  3. Septic abortion, Staphylococcus aureus infection (musculoskeletal infections)
  4. Toxoplasmosis

Adverse effects:

Mnemonic: PAST

  1. Pseudomembranous colitis
  2. Abdominal pain
  3. Skin (rashes, urticaria), Skeletal muscle paralysis (high dose and long-term use)
  4. Toxic megacolon
PGMEE, MRCS, USMLE, MBBS, MD/MS

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