Mnemonic based Clinical Diagnosis of Covid-19

Mnemonic: Covid-MATCH65

1. Covid-19 patient exposure or international travel: 2.5 points
2. Myalgia/Malaise: 1 point
3. Anosmia or Aguesia: 2.5 points
4. Temperature (any reported fever): 0.5 point
5. Coryza/sore throat: -1 point
6. Hypoxia – oxygen saturation <97%: 1 point
7. 65 years or older: 1 point

Scoring assessment:

• <1 = Low risk (0.5%)
• 1-1.5 = Moderate risk (1.5%)
• 2-3.5 = High risk (6%)
• 4-4.5 = Very high risk (20%)
• >5 = Extreme risk (50%)

A cut-off of ≥ 1.5 points was associated with a 92.6% sensitivity and 99.5% negative predictive value (NPV) for COVID-19.

Reference and Image source: Trubiano JA, Vogrin S, Smibert OC, Marhoon N, Alexander AA, Chua KYL, James FL, Jones NRL, Grigg SE, Xu CLH, Moini N, Stanley SR, Birrell MT, Rose MT, Gordon CL, Kwong JC, Holmes NE. COVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2. PLoS One. 2020 Dec 9;15(12):e0243414. doi: 10.1371/journal.pone.0243414. PMID: 33296409; PMCID: PMC7725390.