Acute Undifferentiated Febrile Illness – Mnemonic

Acute undifferentiated febrile illnesses (AUFI) are characterised by fever of less than two weeks’ duration without organ-specific symptoms at the onset.


Mnemonic MA-ESR lists the five main disease groups that cause acute undifferentiated febrile illnesses

a. Malaria: Including all malaria due to Plasmodium falciparum, P vivax, P ovale, P malariae, P knowlesi

b. Arboviral infections: Such as dengue, chikungunya, Japanese encephalitis, Zika, yellow fever

c. Enteric fever: Due to Salmonella enterica serovar Typhi and Paratyphi A, B, C

d. Spirochete infections: Such as leptospirosis and tick-borne or louse-borne relapsing fever

e. Rickettsial infections: Including scrub typhus, murine typhus, spotted fevers

Further reading: Bhargava A, Ralph R, Chatterjee B, Bottieau E. Assessment and initial management of acute undifferentiated fever in tropical and subtropical regions. BMJ. 2018 Nov 29;363:k4766. doi: 10.1136/bmj.k4766. PMID: 30498133.

Write your Viewpoint 💬

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.