Constructing Differential Diagnoses : Mnemonic

doctor differentials


V: Vascular (bleed or blocked), or anything related to hematology

I: Infective or Post-infective

T: Trauma or mechanical factors such as obstructions or pressure.

A: Autoimmune-related or Allergy

M: Metabolic

I: Idiopathic or Iatrogenic

N: Neoplasia

S: Social reasons – child abuse and social deprivation

A: β€œAlcohol”-related issues

B: Behavioral or psychosomatic disorders

C: Congenital problems (entire VITAMINSABCDEK could be applied again in the congenital causes)

D: Degenerative disorders or Drug-related problems

E: Endocrine or exocrine problems

K: Karyotype or genetic disorders.Β 


Zabidi-Hussin ZA. Practical way of creating differential diagnoses through an expanded VITAMINSABCDEK mnemonic. Adv Med Educ Pract. 2016 Apr 22;7:247-8. doi: 10.2147/AMEP.S106507. PMID: 27217805; PMCID: PMC4853007.

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