Definition of Apoptosis Apoptosis is: Origin of the word “apoptosis”: Caspases – Central Regulators of Apoptosis Caspases = Cysteine Aspartate Specific Proteases 2 types of…
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Cellular Adaptations
Hypertrophy, Hyperplasia, Atrophy and Metaplasia are the main four types of cellular adaptations. Adaptations are: Reversible changes In the number, size, phenotype, metabolic activity or functions…
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Endpoints of resuscitation MAP: > or = 65 mmHg Urine output: > 0.5 ml/kg/hr; despite ↓RBF (Renal Blood Flow) it can be normal due to…
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International Surviving Sepsis Campaign has recommended Early Goal Directed Therapy for the management of severe sepsis and septic shock. Recently, three large multicenter studies –…
Explore more Is there no role of Early Goal Directed Therapy (EGDT) in Sepsis and Septic shock?Understanding New Definition of Sepsis (Sepsis-3)
The Sepsis-2 definition used SIRS criteria and the term “Severe sepsis” which has been recently eliminated by the Sepsis-3. The new sepsis definitions recommend using…
Explore more Understanding New Definition of Sepsis (Sepsis-3)Complications of Long Term Dialysis
A) Cardiovascular complications 1. Exacerbation or Precipitation of CHF – Voluminous AV Fistula AV shunting → Decreased TPR → BP fall → Sympathetic stimulation & RAAS activation → Ventricular remodeling…
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Normal puerperium has been already discussed earlier here. A) Immediately after labor within 1 hour Blood pressure and heart rate atleast every 15 minutes Monitor…
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Definition of Puerperium: Period following childbirth during which the body tissues, specially the pelvic organs involute i.e. revert back approximately to the pre-pregnant state both…
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