Pharmacokinetics After oral ingestion, Pregabalin is rapidly absorbed (Tmax 1.3 hr) Bioavailability is >90% and independent of dose Pregabalin is NOT protein bound Vd is 0.4 L/kg Serum pregabalin concentrations are linearly related to dosage Pregabalin is NOT metabolized Pregabalin is primarily excreted unchanged in urine (98%) with a clearance…
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Diabetic? Understanding Bariatric Surgery To Manage Diabetes
Treating diabetes is a constant struggle for many people. Between dieting and keeping insulin cool, it takes a lot of discipline. Something that prevents a lot of people from managing their diabetes is their weight. It’s a vicious cycle that being obese makes diabetes more serious and at the same…
PGMEE, MRCS, USMLE, MBBS, MD/MS
ECG Guide for Surgeons
There is an old saying that two surgeons and an ECG form a double-blind-study. Then, there’s a protocol for surgeons intended for humor: All spikes up: Operate All spikes down: Call Medics All spikes missing: Recently: Call Anesthetist A long time ago: Complete death certificate So, let’s think of heart…
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Choosing a new dentist: 6 factors you need to consider
It can be easy to forget about the health of your teeth until something goes wrong and you’re in excruciating pain. The easiest way to avoid this is brushing twice a day and having regular checkups with your dentist. Therefore, it’s vital to be enrolled with a dentist that you…
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8 Useful Tips for Choosing a Healthcare Provider
If you live in the US, you will know how critical it is to have the right health insurance. Today, many Americans still face the risk of bankruptcy due to a lack of healthcare. Still more of us are also at risk financially because of insufficient coverage. Choosing which provider…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Perioperative Management of Venous thromboembolism (VTE)
Recommended duration of anticoagulant prophylaxis The recommendations are as follows: 1. Provoked DVT (with reversible surgical or nonsurgical provoking factor): 3 months 2. Unprovoked isolated distal DVT (has low risk of recurrence): 3 months 3. Unprovoked proximal DVT or PE: Indefinite therapy if D-dimer positive after 1 month after 3 months of therapy or second VTE…
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The Psychological Impacts Of Drug Addiction
The widespread issue of drug addiction has plagued the world for so long that it’s almost impossible to backtrack where it even started. Regardless, many have found the path to recovery and managed to devote their lives to sobriety, proving that drug addiction can be overcome. That said, when seeking…
PGMEE, MRCS, USMLE, MBBS, MD/MS
Pedicle Screw Insertion Simplified
Anatomy of Vertebral Pedicle Width (narrowest transverse diameter): Narrowest at T4-T5 (4-5 mm) Above and below this level, the width gradually increases to almost double at T1 and T11 (8 mm) Narrowest for lumbar at L2 (two for tiny; 2 X 3 = 6 mm) Increases gradually to L5 (5…