Antiplatelet therapy Aspirin 2-4 non-enteric coated chewable baby aspirins (81 mg each) – buccal absorption is the fastest for platelet inhibition. Initial dose: 150 mg…
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Early vs Delayed Norepinephrine Use in Septic Shock
Norepinephrine has numerous effects in sepsis including veno-constriction (increasing preload), arterial constriction (increasing systemic vascular resistance), positive inotropy, improved cardiac output, and improved renal perfusion.…
Explore more Early vs Delayed Norepinephrine Use in Septic ShockWhy to not defibrillate Asystole ?
What is asystole? Asystole is a state of no cardiac electrical activity. It is seen as a “flat-line” in ECG monitor. However, other possible causes…
Explore more Why to not defibrillate Asystole ?Septic Shock Fluid Resuscitation
Endpoints of resuscitation MAP: > or = 65 mmHg Urine output: > 0.5 ml/kg/hr; despite ↓RBF (Renal Blood Flow) it can be normal due to…
Explore more Septic Shock Fluid ResuscitationIs there no role of Early Goal Directed Therapy (EGDT) in Sepsis and Septic shock?
International Surviving Sepsis Campaign has recommended Early Goal Directed Therapy for the management of severe sepsis and septic shock. Recently, three large multicenter studies –…
Explore more Is there no role of Early Goal Directed Therapy (EGDT) in Sepsis and Septic shock?Understanding New Definition of Sepsis (Sepsis-3)
The Sepsis-2 definition used SIRS criteria and the term “Severe sepsis” which has been recently eliminated by the Sepsis-3. The new sepsis definitions recommend using…
Explore more Understanding New Definition of Sepsis (Sepsis-3)Postpartum Eclampsia : Case Discussion
History 23yrs/F non-diabetic, non-hypertensive, non-smoker, non-alcoholic primigravida was admitted to Obstetric ward on with the chief complaints of: Cessation of menstruation X 9 months Decreased…
Explore more Postpartum Eclampsia : Case DiscussionAcute Pancreatitis – Case Discussion
Cases of Acute Pancreatitis Case 1 32 years old male came to emergency department with complaint of: Upper abdominal pain X 3 days Vomiting X…
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