Mnemonic: 2 out of ABCDEFG
1. Axillary or inguinal freckling
2. Bone lesions (sphenoid dysplasia, tibial pseudoarthrosis)
3. Cafe au lait macules/spots (>/= 6 in number; >/= 5 mm in prepubertal and >/= 15 mm in postpubertal)
4. Dermatologic neurofibroma
5. Eye hamartomas/Lisch nodules >/= 2
6. Family history (first degree relative)
7. Glioma of optic nerve
The diagnosis of NF1 requires atleast 2 of 7 NIH criteria.
The severity of alcoholic hepatitis can be assessed using a number of simple quantitative indices (Maddrey score, Meld score, Combined clinical and laboratory index). Of these, the Maddrey Discriminant Function (MDF) is the simplest. Maddrey score = 4.6 X (prolongation of prothrombin time above control in seconds) + Total bilirubin…
If the QRS complex is wide (>0.12 s/>3 small squares), the ventricular activity may be arising from the ventricle conducting system. caused by a ‘bundle branch block’. WiLLiaM MaRRoW (classic mnemonic) Wi – V1LL – LBBBM – V6 M – V1RR – RBBBW – V6 ViLLheiM MaRRooN (more accurate) V…
Definition        Failure of bone marrow to produce peripheral blood cells and its progenitors Etiology The following illustration gives a brief idea about the etiological factors of aplastic anemia Now going into each etiological factor: – Autoimmune diseases: – Either they affect all the lineages (autoimmune aplastic anemia) or a single…