We have simplified the information above as following:
Category A: Adequate Anthropoid (Human) studies and Absolutely safe (No risk in controlled human studies)
Category B: Bounded (limited) human studies and safe in Beast (animal) studies; Better to use (No risk in other studies)
Category C: Catastrophic effects in animals and Controlled studies inadequate in humans; Could use (Risk not ruled out)
Category D: Dangerous effects in humans; Don’t use it unless Despair (Positive evidence of risk)
Category X: Cross it out (Contraindicated in pregnancy)