We have 1 heart and 2 lungs.
a. B1 – heart
b. B2 – bronchial wall
Cardioselective (B1) vs Non-selective (B1 and B2) beta blockers
Beta blockers with 1st letter from A to N are Cardioselective:
- Acebutolol
- Atenolol
- Bispoprolol
- Betaxolol
- Celiprolol
- Esmolol
- Metoprolol
- Nebivolol
Nebivolol = NO donor
Beta blockers with 1st letter from O to Z are Non-selective:
- Pindolol
- Propanolol
- Sotalol
- Timolol
Both alpha and beta blockers: Labetalol, Bucindolol, Carvedilol
Beta blockers with Intrinsic sympathomimetic activity (ISA) or parital agonists
Mnemonic: Buci & Celi took Cart, Pen, Pin to Ace Lab.
- Buci-ndolol
- Celi-prolol
- Cart-elol
- Pen-butolol, Ox-pren-olol, Al-pren-olol
- Pindolol
- Acebutolol
- Labetalol
Beta-blockers with Membranse stabilizing activity (MSA)/Na+ blocking action (Local anesthetic/Anti-arrhythmic activity)
Mnemonic: Professor Meto took Pin to Ace Lab.
- Propanolol (maximum MSA)
- Metoprolol
- Pindolol
- Acebutolol
- Labetalol
Carvedilol is an exception to this rule!