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Mnemonics, Simplified Concepts & Thoughts

“5-Ps” Mnemonic for Preoperative Antibiotic Prophylaxis

Epomedicine, Jul 10, 2025Jul 10, 2025

Last updated on July 10, 2025

Preoperative antibiotics
AI generated and Modified

Potential indications for antibiotic prophylaxis before surgical procedure are:

1. Penetration into gastrointestinal, respiratory and genital lumens

  • Clean-contaminated procedures

2. Prosthesis

  • Surgical meshes
  • Orthopedic hardwares
  • Breast and penile implants

3. Presence of infection

  • Contaminated surgeries such as elimination of septic foci and manipulations of infected tissues

4. Prolonged surgery

  • Additional risk factor

5. Poor patient immunity

  • Additional risk factor

Reference: Hasanin A, Mostafa M. The “5-Ps” Mnemonic for Antibiotic Prophylaxis Before Surgery. Anesth Analg. 2025 May 7. doi: 10.1213/ANE.0000000000007596. Epub ahead of print. PMID: 40333465.

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PGMEE, MRCS, USMLE, MBBS, MD/MS AnesthesiaGeneral Surgery

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Epomedicine. “5-Ps” Mnemonic for Preoperative Antibiotic Prophylaxis [Internet]. Epomedicine; 2025 Jul 10 [cited 2025 Jul 10]. Available from: https://epomedicine.com/medical-students/5-ps-mnemonic-for-preoperative-antibiotic-prophylaxis/.

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