Mnemonic: SACHS GO 1. Spots in macula (Cherry red spots) 2. Ashkenazic jews 3. CNS degeneration 4. Hexosaminidase A enzyme deficiency 5. Storage disorder 6. GM2 ganglioside accumulation 7. Onion skin appearance of lysosomes Further reading:
Author: Epomedicine
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Retatrutide Peptide: A Multifaceted Tool in Metabolic and Cellular Research
Studies suggest that Retatrutide is an emerging peptide of considerable interest in the domain of metabolic research due to its complex pharmacological profile. Research indicates that with multiple functional properties, Retatrutide might offer a promising avenue for understanding metabolic processes, energy homeostasis, and various cellular mechanisms. This article explores the…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Antidepressants : Mnemonics
Classification and Mechanism of Action Acronyms: Mnemonic: TRIM 3N 3S Class Mechanism Drugs Side effects TCA Blocks reuptake of 5-HT, NA & other receptors (H1, ACh, α1, Voltage sensitive Na+ channel) Mnemonic: ANTI-DeP-C1. Amitryptiline, Amoxapine2. Nortryptiline3. Trimipramine4. Imipramine5. Doxepin, Desipramine, Dothiepin6. Protryptiline7. Clomipramine M1 blockade: Muscarinic anticholinergic side-effects α1 blockade:…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Wernicke-Korsakoff syndrome : Mnemonic
Wernicke-Korsakoff syndrome is the most serious form of thiamine deficiency in patients diagnosed with alcohol use disorder. Thiamine deficiency in alcoholics (Wernicke-Korsakoff syndrome) results in degeneration of the medial-dorsal nucleus of thalamus, mamillary bodies, hippocampus and vermis of cerebellum. Mnemonic: COAT RACK Wernicke’s Encephalopathy (Acute phase) Korsakoff’s Psychosis (Chronic phase)
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The Role of Physical Therapy in Managing Piriformis Syndrome
Piriformis syndrome is one in which the piriformis muscle situated at the gluteal region of the body applies pressure on the sciatic nerve, causing discomfort, paresthesia, and Paraesthesia along the course of the nerve. The piriformis is a hip-preserving muscle, and any form of inflammation of this muscle is going…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Unhappy Triad of O’Donoghue : Mnemonic
O’Donoghue unhappy triad is occurrence of 3 different soft tissue injuries of knee simultaneously. It includes: Mnemonic: MAM Mechanism: valgus stress with rotation of the knee Later on, more studies emerged showing that injuries in the lateral meniscus were more prevalent than injuries in the medial meniscus. The unhappy triad…
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How an Unstable Home Life Affects a Child’s Development
Stable homes serve as the bedrock for a happy, fulfilling childhood. When children are exposed to environments that are unpredictable, unstable, or neglectful, many aspects of their well-being are put at risk. Emotional, physical, and psychological needs are all major parts of what comprises well-being, especially during key developmental periods…