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Mnemonics, Simplified Concepts & Thoughts

PGMEE, MRCS, USMLE, MBBS, MD/MS

Working formulation of NHL (Mnemonic)

Epomedicine, Jan 16, 2019Feb 26, 2019

All follicular except large cell: Low grade All diffuse: Intermediate grade Blastic and non-cleaved: High grade

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Blog mental health UN

Mental Health Issues in UN Peacekeeping (Infographics)

Dr. Sulabh Kumar Shrestha, MS Orthopedics, Dec 22, 2018Mar 28, 2019

This was done as a final presentation for the webinar course – “Social media and United Nations”. I have tried to create this infographic using microsoft powerpoint, free images and icons. Platform: Microsoft powerpoint Slide size: 30 inch X 10 inch Type of infographic: Statistical + Informational Title: Mental Health…

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PGMEE, MRCS, USMLE, MBBS, MD/MS tyrosinemia

Tyrosinemia Enzymes : Mnemonic

Epomedicine, Aug 12, 2018Aug 12, 2018

Mnemonic: FAHeem TATtooes because of Histrionic Personality Disorder (HPD) Tyrosine is necessary for biosynthesis of catecholamines, thyroid hormones and melanin pigment. 1. Tyrosinemia type I (Tyrosinosis/Hepatorenal tyrosinemia): Enzyme defect: FAH (Fumaryl-acetoacetate hydroxylase) Last enzyme in the cycle Cabbage like odor Hepatocellular carcinoma Renal tubular acidosis Peripheral neuropathy 2. Tyrosinemia type II…

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PGMEE, MRCS, USMLE, MBBS, MD/MS inhibition_Lineweaver_Burk

Competitive, Non-competitive and Uncompetitive Inhibitors

Epomedicine, Aug 10, 2018Aug 18, 2024

Vmax is the maximum velocity, or how fast the enzyme can go at full ‘‘speed.’’ Vmax is reached when all of the enzyme is in the enzyme–substrate complex. Km is the substrate concentration at which v = 1/2 Vmax. Km approximately describes the affinity of the substrate for the enzyme….

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PGMEE, MRCS, USMLE, MBBS, MD/MS fatty-acid-oxidation

Beta-oxidation of Fatty Acids : Simplified

Epomedicine, Jul 31, 2018

Fatty Acid Activation (Cytoplasm) Before undergoing oxidation, fatty acid must be activated first by conversion into Acyl-CoA by the action of Fatty Acyl-CoA synthase (thiokinase). ATP is converted to AMP (not ADP) – 2 ATP equivalent used Uses Mg2+ as cofactor, Co-ASH and ATP Sites of Beta-oxidation A. Mitochondria: Short/Medium…

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PGMEE, MRCS, USMLE, MBBS, MD/MS acetylcoa carboxylase

Fatty Acid Synthesis : Simplified

Epomedicine, Jul 30, 2018

Enzymes: Fatty acid synthase (6 enzymes and 1 Acyl carrier protein molecule) Acetyl-CoA carboxylase (rate-limiting enzyme) Starting material: For palmitate synthesis: Acetyl-CoA For odd number carbon long chain fatty acid synthesis: Propionyl-CoA 2 Carbon donor: Malonyl-CoA (donates 2 C and 1 C is thrown out as CO2) Site: Cytosol Citrate…

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PGMEE, MRCS, USMLE, MBBS, MD/MS fatty acid

Structure of Fatty acids and Derivatives : Simplified

Epomedicine, Jul 29, 2018Jul 29, 2018

Structure Saturated fatty acid: Single bond (“S” for saturated and single bond) Unsaturated fatty acid: Double bond(s), i.e. “D” for Double bonds, Decreased melting temperature and Decreased atherosclerotic risk (by decreasing LDL) Trans-fatty acid: Unsaturated fatty acid which act like saturated fatty acid (hydrogenation of unsaturated fatty acid) Nomencleture: C…

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PGMEE, MRCS, USMLE, MBBS, MD/MS hypothalamus hunger satiety

Orexigenic and Anti-orexigenic peptides : Mnemonic

Epomedicine, Jul 28, 2018

Orexigenic (Appetite stimulant) peptides Mnemonic: When you see MANGOEs, you feel like eating. MCH (Melanocyte Conentrating Hormone) AGRP (Agouti Related Peptide) NPY (Neuropeptide Y), Noradrenaline GnRH, GABA, Galanin, Ghrelin Orexins A and B Endorphins, Endocannabinoids Anti-orexigenic (Appetite supressant) peptides Mnemonic: NO BLACk PIGS Neurotensin Oxytocin, Oxyntomodulin Bombesin Leptin Alpha-MSH (POMC derivative), Amylin,…

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