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Avascular Necrosis (Osteonecrosis) of Various Bones : Stages and Management

Epomedicine, Jul 23, 2024Jul 23, 2024

Propensity

  1. Subarticular regions:
    • Lie at the most distant parts of the body’s vascular territory
    • Largely enclosed by cartilage, giving restricted access to blood vessels
    • Endarterioles with limited collateral connections
  2. Marrow and bone cells:
    • Vascular sinusoids unlike arterial capillaries have no adventitial layer and their patency is determined by the volume and pressure of the surrounding marrow tissue
osteonecrosis of humerus head
Jmarchn, CC BY-SA 3.0, via Wikimedia Commons

Stages and Management

StagesHip (modified Ficat-Arlet)Shoulder (Cruess)Lunate (Lichtman)Knee (Koshino)Scaphoid (Herbert and Lanzetta)Management
0 – Silent+NWB joints – Immobilization, NSAIDs

WB joints –
a. Realignment osteotomy
b. Core decompression +/- bone grafting or MSC therapy
I – Suggestive clinically and MRI+++++As above

NWB joints – Arthrodesis

Kienbock (ulnar negative variance): Joint levelling procedure
II – Sclerosis or Subchondral cysts+; IIb – Subchondral fracture (Crescent sign)++; IIb – Subchondral fracture++As above
III – Subchondral collapse and Sphericity loss+++; IIIa – rotational dislocation of scaphoid absent; IIIb – rotational dislocation of scaphoid present (ring sign)++Arthrodesis
Partial or total joint replacement

Kienbock IIIb – Proximal row carpectromy
IV – Space narrowing and Secondary arthrosis++; humeral head+++As above
V – Space narrowing and Secondary arthrosis+; also glenoidAs above
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PGMEE, MRCS, USMLE, MBBS, MD/MS Musculoskeletal systemOrthopedics

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Epomedicine. Avascular Necrosis (Osteonecrosis) of Various Bones : Stages and Management [Internet]. Epomedicine; 2024 Jul 23 [cited 2025 Dec 26]. Available from: https://epomedicine.com/medical-students/avascular-necrosis-osteonecrosis-of-various-bones-stages-and-management/.

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