Norepinephrine has numerous effects in sepsis including veno-constriction (increasing preload), arterial constriction (increasing systemic vascular resistance), positive inotropy, improved cardiac output, and improved renal perfusion.…Explore more Early vs Delayed Norepinephrine Use in Septic Shock
Endpoints of resuscitation MAP: > or = 65 mmHg Urine output: > 0.5 ml/kg/hr; despite ↓RBF (Renal Blood Flow) it can be normal due to…Explore more Septic Shock Fluid Resuscitation
International Surviving Sepsis Campaign has recommended Early Goal Directed Therapy for the management of severe sepsis and septic shock. Recently, three large multicenter studies –…Explore more Is there no role of Early Goal Directed Therapy (EGDT) in Sepsis and Septic shock?
The Sepsis-2 definition used SIRS criteria and the term “Severe sepsis” which has been recently eliminated by the Sepsis-3. The new sepsis definitions recommend using…Explore more Understanding New Definition of Sepsis (Sepsis-3)
History 23yrs/F non-diabetic, non-hypertensive, non-smoker, non-alcoholic primigravida was admitted to Obstetric ward on with the chief complaints of: Cessation of menstruation X 9 months Decreased…Explore more Postpartum Eclampsia : Case Discussion
Terminologies Related with Status Epilepticus 1. Seizure: Abnormal or excessive neuronal discharge causing a transient disturbance of cerebral function. 2. Epilepsy: A condition characterized by recurrent (≥2)…Explore more Status Epilepticus and Neonatal seizures : Updated Management
SIRS criteria are mostly used as a screening tool to identify patients that may need further workup for sepsis and severe sepsis. In the emergency…Explore more The Continuum: SIRS, Severe Sepsis and Septic Shock
Pre-eclampsia is a disorder of pregnancy, characterized by hypertension (BP > 140/90 mmHg measured 2 times with interval ≥ 6 hours) and proteinuria (urinary excretion…Explore more Pritchard regimen (MgSO4) in PIH