Vancouver style or NLM style of referencing is commonly used in medicine to cite other’s work in the text. General Rules 1. Reference numbers: Indicate the reference using arabic numerals inside [square] or (curved brackets) or as superscripts – use the same style throughout your scientific writing. Reference numbers must…
Author: Dr. Sulabh Kumar Shrestha, MS Orthopedics

History and Physical Examination Format
HISTORY 1. General Information: 2. Chief complaints: Example: Lower abdominal pain X 2 daysNausea and vomiting X 1 day 3. History of Presenting Illness: “OPQRST” for each symptoms Negative history: Treatment received for the complaint Review of systems: may or may not be related to chief complaint – include only…

Acute STEMI Management – Mnemonic based approach
60 year old smoker patient came with epigastric pain and shortness of breath for 4 hours. The patient was tachypneic with SpO2 90%. Other vital signs were relatively stable. ECG was done, Troponin I was positive and CK-MB was 100 IU/l. What is there in ECG above? ST elevation and…

Fever and Rash : Mnemonic Based Approach
Seven Killer Causes of Fever and Rash Mnemonic: SMARTTT Sepsis Meningococcemia Acute endocarditis Rocky mountain spotted fever Toxic erythemas Toxic epidermal necrolysis Travel-related infections Onset of Rash with “X” Days of Fever Mnemonic: Very Sick Person Must Take Double Eggs Varicella (Chicken pox): 1st day (rash is often 1st sign…

Short Approach to SVT and AVNRT management
This is an ECG from a patient who came with a complaint of palpitation: Analyze the ECG: Rhythm: Regular Heart rate: Around 170/min QRS: Around 0.08 s i.e. ≤0.1 s (narrow QRS complex) ECG diagnosis: Regular Supraventricular Tachycardia (SVT) Now, look for P waves – There are no P waves In…

Is Nitrofurantoin effective for Skin infections?
Recently, a wound swab culture and sensitivity reported an E.coli sensitive to Nitrofurantoin. But will it really be helpful in the wound infection? Without a doubt, literatures claim that the sole use of the drug is in the treatment of Urinary Tract Infection (UTI), as after oral or intravenous (i.v.)…

DNA Replication Explained With Zipper Model
Imagine DNA as a zipper Prokaryotic DNA as a zipper with single slider (single origin of replication) and Eukaryotic DNA as a zipper with two sliders (multiple origin of replication). Zipper teeth: Purines and pyrimidine bases Complementary teeth pair: Complementary base pairs attached by hydrogen bonds Top stops: Origin of…

Lysosomal Storage Disorders Made Easy
Among the common lysosomal storage disorders: Two of them are Mucopolysaccharidoses (Hunter and Hurler syndrome) Pompe’s disease is Glycogen Storage Disease. Others are Sphingolipidoses. Inheritance of Lysosomal Storage Diseases All are inherited as Autosomal Recessive (AR) condition except: Hunter syndrome (X-linked recessive) Fabry’s disease (X-linked recessive) Higher risk in Ashkenazi…