Jugular venous pulse (JVP) waveforms a – Atrial contraction (RA) c – Closure and Curving of tricuspid valve into RA x – atrial relaXation v – Venous filling of right atrium (RA) y – atrial emptYing Distinguishing JVP from Internal carotid pulsation Mnemonic: POLICE Palpation: Non-palpable Occlussion: Readily occludable Location:…
Author: Dr. Sulabh Kumar Shrestha, MS Orthopedics
He is the section editor of Orthopedics in Epomedicine. He searches for and share simpler ways to make complicated medical topics simple. He also loves writing poetry, listening and playing music.
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Visual cycle – Simplified
11-cis-retinal combines with opsin protein to form rhodopsin. Light stimulates conversion of rhodopsin bound 11-cis-retinal to all-trans-retinol (all-trans-retinol is transported from photoreceptor cells to retinal pigment epithelium), which subsequently dissociates from opsin (bleaching), leading to membrane depolarization and initiation of action potential in photoreceptors in the neural retina. Once in…
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United Nation’s Peacekeeping Mission – A Doctor’s Story
In a very short notice to be prepared, we left home for the residential pre-deployment training on January, 2018. In the freezing cold of the winter, we started our day in the early morning with P.T (Physical Training). We attended various sessions, which made us familiar on the topics of…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Protein C and S pathway – Mnemonic
Factor Va and VIIIa are different in coagulation cascade. They are the co-factors for factor Xa and IXa respectively. Another mnemonic: protein C Cuts Coagulation by Cutting Cofactors (Va and VIIIa) Protein S is cofactor for protein S. Protein C and S pathway using the mnemonic: Time To: Thrombin (factor…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Hematopoietic growth factors list with mnemonics
a. SCF (Steel factor): Multipontent stem cells b. IL-3: Myeloid stem cells (“3” turned down looks like “m“) c. IL-7: Lymphoid stem cell (“L” turned up looks like “7“) d. GM-CSF (Granulocyte macrophage Colony stimulating factor): Myeloid lineage (Erythrocytes, Thrombocytes, Granulocytes and Monocytes) Pharmaceutical: Sargramostim e. G-CSF: Granulocytes (Neutrophil, Eosinophil,…
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Acyclovir Post-exposure Prophylaxis for Varicella: Is it helpful?
Dose: 80 mg/kg/day in 4 divided doses for 7 days; maximum 800 mg 4 times a day Time to start prophylaxis: 7-10 days after exposure (late incubation period) Indication: People without evidence of immunity and with contraindications for varicella vaccination (VZIg) Results from some studies Among 27 children in the…
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Doctor-Patient mistrust may be expensive to patients
The risks of malpractice litigation are proving to be harmful to the US health system; the number of practitioners practicing defensive medicine is increasing. “Defensive medicine” is a practice where a doctor suggests clinical investigations or remedies that do not have to be the best choice for the patient. The main role…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Coomb’s test : Mnemonic
Components of Coomb’s test: Mnemonic: ABCD A: Antibody (to be detected) B: Blood antigen (RBC) C: Coomb’s reagent (Anti-antibody) D: Detect agglutination Direct Coomb’s/Antiglobulin test (DAT or DCT): Mnemonic: In DAT/DCT we take A+B from patient and add C [(A+B) + C] Another Mnemonic: DCBA (Direct Coomb’s detect Blood Bound…