CAUSES OF INCREASED PIGMENTATION
S: Systemic sclerosis
H: Hemochromatosis 1*
A: Alkaptonuria
K: Kala azar
A: Arsenicosis
H: Hemochromatosis 2*
A: Addison’s
N: Nelson’s
D: Drugs
- Amiodarone
- Busulfan
- Bleomycin
- Phenytoin
- Phenothiazine
- Psoralen
SADDLE NOSE
S: Sarcoid, Syphilis congenital, Sponastrine dysplasia, Steward granuloma (extranodal NK/T lymphoma, EBV+), Stickler syndrome (chromos 12 mutation, short nose, & stature, submucous palatal cleft, myopisa and hearing loss, joint hypermobility)
A: Alpha L I idurinidase deficiency, Anticoagulation [Warfarin]
D: Dysplasia Otospondylo megaepiphyseal and Rhizomelic
D: Deletion 7p
L: Lowe syndrome
Et al: Wegener, Polychondritis, I cell disease, Rothmund Thomson, Cocaine abuse
LOOK at the MOUTH & remember what you can diagnose
M: Mallampati (OSA), Marfan, Macroglossia (Beckwith Wiedemann syndr.), M5 (Monocytic AML), Muir’s crackle (laryngeal crepitus), Micrognathia & Macrognathia, Miura Cooperman syndrome (retrusion of the mandible causing tongue uvula impingement)
O: Odor (bronchiectasis, lung abscess), OHL (oral hairy leukoplakia in HIV = EBV)
U: Ulcers, Uvula (Bifid: Loeyz Dietz syndrome, Pallister Hall syndrome)
T: Tongue, Tonsils, Teeth, Tardive dyskinesia, Trotter syndrome (nasopharyngeal ca with unilateral deafness, + Trigeminal nerve neuralgia)
H: Hypertrophic gums (ciclosporin, nifedipine, phenytoin, myelomonocytic leukemia, Wegener’s), HOCM (high arch palate, pes cavus, kyphoscoliosis), Heavy chain disease (Franklin g heavy chain, palatal edema), Hemorrhage (ITP, aplastic anemia), Hemorrhagic gingivitis (scurvy)
MOUTH ULCERS
- Arthritis (Reiter syndrome), Aphthous ulcers, Appliances
- Behcet’s disease, B12 deficiency, Burns
- Crohn’s, Coeliac disease, Chickenpox, Cancer & Mucositis
- Drugs: Brufen & NSAIDs, beta blockers, nicorandil, PTU, Alendronate, Cytotoxics & Diabetes
- Erythema multiform, Epidermolysis bullosa
- F” forget not: pemphigus vulgaris & pemphigoid, Febrile neutrophilic dermatosis (Sweet’s syndrome)
- GPA (Wegener), GCA, PAN, & Glucagonoma
- Hand Foot Mouth disease, HIV
- Iron deficiency
- Johnson (Stevens Johnson Syndrome SJS)
- KO: Trauma
- Lupus, Leishmaniasis, Lichen planus, Linear IgA disease (cluster of jewels, string of pearls)
MBChB (O’Porto Univ.), Dip HIV Man (CMSA), DTM&H (Wits), DipPEC (CMSA), Dip Internal Medicine
(CMSA), M. Med. Clinical Pharm [Cum Laude] (Univ. Pretoria), FCP (CMSA). Hard worker, Reliable, Team player, Family man.