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Tay Sach’s Disease : Mnemonic

Mnemonic: SACHS GO

1. Spots in macula (Cherry red spots)

2. Ashkenazic jews

3. CNS degeneration

4. Hexosaminidase A enzyme deficiency

5. Storage disorder

6. GM2 ganglioside accumulation

7. Onion skin appearance of lysosomes

United States, National Institutes for Health, Public domain, via Wikimedia Commons
HexA gene is located on 15q

Further reading:

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