1. Duration: ≥1 months 2. ≥1 of Schneider’s 1st rank symptoms: Mnemonic: ABCDE a. Auditory hallucinations: Voices heard arguing (3rd person), Thought echo, Running commentary b. Bizzare delusions: Voices coming from some part of the body c. Control (Delusion of control): Somatic, Impulse, Volition, Affect (SIVA) d. Delusional perception: A non-hallucinated/true perception…
Category: PGMEE, MRCS, USMLE, MBBS, MD/MS
Medical knowledge in bullet points with understandable language, simplified images and graspable mnemonics.
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Heart Sounds – Abnormal
The basic clinical examination of the Cardiac System is by Auscultation (listening to the sounds made by the heart). As explained in the previous article physiological sounds made in each cardiac cycle viz. S1 and S2 due to the closure of the Atrio-Ventricular Valves and Outlet Valve in synchrony. Please…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Embryology of Eye : Mnemonic
Surface ectoderm derivatives Mnemonic: LEVeL Lens Epithelium All ocular adnexa including mebomian gland and glands of Zeis and Moll Skin Cornea Conjunctiva Vitreous (portion) Lacrimal glands and drainage system Neuro-ectoderm (Optic vesicle and cup) derivatives Mnemonic: MORE Muscles of pupil (constrictor and dilator pupillae) Optic nerve Retinal pigment epithelium Epithelium…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Sarcomere Structure : Mnemonic
Remember the sequence: Zahir Is A Hungry Man Z line (Zwischen = between [German]) I band A band H zone M line Z is the final alphabet: Z lines represents the end of sarcomere M for middle: M line represents the midline of sarcomere I is a thin letter: I…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Working formulation of NHL (Mnemonic)
All follicular except large cell: Low grade All diffuse: Intermediate grade Blastic and non-cleaved: High grade
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Tyrosinemia Enzymes : Mnemonic
Mnemonic: FAHeem TATtooes because of Histrionic Personality Disorder (HPD) Tyrosine is necessary for biosynthesis of catecholamines, thyroid hormones and melanin pigment. 1. Tyrosinemia type I (Tyrosinosis/Hepatorenal tyrosinemia): Enzyme defect: FAH (Fumaryl-acetoacetate hydroxylase) Last enzyme in the cycle Cabbage like odor Hepatocellular carcinoma Renal tubular acidosis Peripheral neuropathy 2. Tyrosinemia type II…
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Competitive, Non-competitive and Uncompetitive Inhibitors
Vmax is the maximum velocity, or how fast the enzyme can go at full ‘‘speed.’’ Vmax is reached when all of the enzyme is in the enzyme–substrate complex. Km is the substrate concentration at which v = 1/2 Vmax. Km approximately describes the affinity of the substrate for the enzyme….
PGMEE, MRCS, USMLE, MBBS, MD/MS 
Beta-oxidation of Fatty Acids : Simplified
Fatty Acid Activation (Cytoplasm) Before undergoing oxidation, fatty acid must be activated first by conversion into Acyl-CoA by the action of Fatty Acyl-CoA synthase (thiokinase). ATP is converted to AMP (not ADP) – 2 ATP equivalent used Uses Mg2+ as cofactor, Co-ASH and ATP Sites of Beta-oxidation A. Mitochondria: Short/Medium…